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Open AccessMetformin hydrochloride entrapment in sorbitan monostearate for intestinal permeability enhancement and pharmacodynamics
Penetration enhancement of metformin hydrochloride via its molecular dispersion in sorbitan monostearate microparticles is reported. This represents basic philosophy to maximize its entrapment for maximum pene...
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Article
Open AccessNovel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases
TAL-effector nucleases (TALENs) are attractive tools for sequence-specific genome modifications, but their delivery still remains problematic. It is well known that the presence of multiple sequence repeats in...