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within Waseem Qasim Remove this filter Medicine & Public Health Remove this filter Internal Medicine Remove this filter

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  1. Chapter

    Off-the-Shelf Allogeneic CAR-T Cells or Other Immune Effector Cells

    “Off-the-shelf” allogeneic CAR TCRab T cells and other immune effector cells, such as natural killer (NK) or gamma delta (gd) T cells, can be premanufactured from healthy donors and may offer alternatives to a...

    Stephane Depil, Waseem Qasim in The EBMT/EHA CAR-T Cell Handbook (2022)

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  2. Article

    Open Access

    Base-edited CAR T cells for combinational therapy against T cell malignancies

    Targeting T cell malignancies using chimeric antigen receptor (CAR) T cells is hindered by ‘T v T’ fratricide against shared antigens such as CD3 and CD7. Base editing offers the possibility of seamless disrup...

    Christos Georgiadis, Jane Rasaiyaah, Soragia Athina Gkazi, Roland Preece… in Leukemia (2021)

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  3. No Access

    Article

    Hematopoietic stem cell transplantation for cytidine triphosphate synthase 1 (CTPS1) deficiency

    Zohreh Nademi, Robert F. Wynn, Mary Slatter… in Bone Marrow Transplantation (2019)

  4. No Access

    Article

    Gene Therapy for Primary Immunodeficiencies: Current Status and Future Prospects

    Gene therapy using autologous haematopoietic stem cells offers a valuable treatment option for patients with primary immunodeficiencies who do not have access to an HLA-matched donor, although such treatments ...

    Waseem Qasim, Andrew R. Gennery in Drugs (2014)