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Open AccessSuppressing miR-199a-3p by promoter methylation contributes to tumor aggressiveness and cisplatin resistance of ovarian cancer through promoting DDR1 expression
Discoidin Domain Receptor 1 (DDR1) belongs to the family of collagen receptor tyrosine kinases that confers the progression of various cancers. Aberrant expression of DDR1 was detected in several human cancers...
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Article
The application of a three-column internal fixation system with anatomical locking plates on comminuted fractures of the tibial plateau
The purpose of this study was to describe the operative procedures and clinical outcomes of a new three-column internal fixation system with anatomical locking plates on the tibial plateau to treat complex thr...
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Article
Effects of manganese deficiency on serum hormones and biochemical markers of bone metabolism in chicks
In order to investigate the effect of manganese (Mn) deficiency on bone metabolism in chicks, ninety 1-day-old male Arbor Acre chicks were randomly divided into 3 groups and each group were given a diet having...
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Article
Effects of amiodarone on transmural dispersion of ventricular effective refractory periods across myocardial layers in the normal and hypertrophic canine heart
The effects of amiodarone on transmural dispersion of ventricular effective refractory periods (ERPs) in the normal and hypertrophic canine heart were investigatedin vivo. By using the programmed stimulation prot...
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Article
Effects of simvastatin on NF-κB-DNA binding activity and monocyte chemoattractant protein-1 expression in a rabbit model of atherosclerosis
To observe the effects of simvastatin on nuclear factor kappaB (NF-κB)-DNA binding activity and on the expression of monocyte chemoattractant protein-1 (MCP-1) in atherosclerotic plaque in rabbits and to explo...
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Article
Expression of telomerase subunits in gastric cancer
To detect the expression of telomerase subunits (human telomerase reverse transcriptase, human telomerase associated protein 1 and human telomerase RNA) in gastric cancer and to examine the role that different...
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Article
Changes of monophasic action potential duration and effective refractory period of three layers myocardium of canine during acute ischemiain Vivo
The effect of acute ischemia on the electrophysiological characteristics of the three layers myocardium of caninein vivo was investigated. Twelve canines were divided into two groups randomly: acute ischemia (AI)...
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Article
Value of echocardiography for evaluation of the flow-dependent epicardial coronary vasodilationIn Vivo
To assess the value of echocardiography for detection of the flow-dependent epicardial coronary vasodilation, the changes in internal diameter of the left anterior descending coronary arteries (LAD) induced by...
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Article
Effect of lidocaine and amiodarone on transmural heterogeneity of ventricular repolarization in isolated rabbit hearts model of sustained global ischemia
To study the effect of of lidocaine and amiodarone on the transmural heterogeneity of ventricular repolarization in isolated rabbit hearts model of sustained global ischemia and to explore the mechanisms under...
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Article
Sex difference in the repolarization currents of rabbit ventricular cells
The current difference between male and female rabbit ventricular myocytes was investigated for elucidating the mechanism of longer QT interval and higher incidence of drug-associated torsade de pointes in fem...
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Article
Quantitative assessment of right ventricular systolic function by the analysis of right ventricular contrast time-intensity curve
To study reliability and reliable indices of quantitative assessment of right ventricular systolic function by time-intensity curve (TIC) with right ventricular contrast, 5% sonicated human albumin was injecte...
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Article
TLR2 mRNA upregulation in ischemic lobes in mouse partial hepatic ischemia/reperfusion injury model
To investigate TLR2 (Toll-like receptor 2) mRNA expression in ischemic hepatic lobes under the condition of partial hepatic ischemia/reperfusion injury in BALB/c mice and its relationship with liver function i...
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Article
Effect of autonomic nervous system on the transmural dispersion of ventricular repolarization in intact canine
The effect of the autonomic nerves on the transmural dispersion of ventricular repolarization in intact canine was investigated. By using the monophasic action potential (MAP) recording technique, monophasic a...
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Article
Detection of telomerase activity and the expression of telomerase subunits in the patients with acute myelogenous leukaemia
Telomerase activity and the expression of telomerase subunits (for example, telomerase reverse transcriptase and telomerase associated protein 1 and telomerase RNA component) of peripheral white blood cells we...
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Article
Polymorphisms of IL-4, IL-4Rα, and AICDA genes in adult allergic asthma
The relationship between 3 polymorphisms sites [interleulin-4 (IL-4), IL-4 receptor (IL-4R) α chain and activation-induced cytidine deaminase (AICDA)] and adult allergic asthma in China was studied. By using c...
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Article
Experimental study of the effect of autonomic nervous system on the transmural dispersion of ventricular repolarization under acute myocardial ischemiain vivo
The effect of the autonomic nerves on the transmural dispersion of ventricular repolarization (TDR) under acute myocardial ischemia in intact canine was investigated. Using the monophasic action potential (MAP...
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Article
Study on apoptosis and expression of P53, Bcl-2, bax in cardiac myocytys of congestive heart failure induced by ventricular pacing
The apoptosis and the expression of p53, bcl-2 and Bax in myocytes of chronic rapid ventricular pacing-induced congestive heart failure (CHF) in rabbits were investigated. The CHF rabbit model (P,n=7) was establi...
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Article
The effect of T-2 toxin on IL-1β and IL-6 secretion in human fetal chondrocytes
The effects of T-2 toxin on IL-1β and IL-6 secretion in human fetal chondrocytes in vitro were investigated. The evaluation is realised on primary monolayer culture of human fetal epiphyseal chondrocytes with ...
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Article
Über EKG-Kennzeichungen der atrioventrikulären akzessorischen Leitungsbahnen von Rechtsmittel septa und Linksmittelsepta
In der Studie wurden 20 Patienten mit AV-Reentry-Tachykardie unter Einbezug einer mittelseptalen gelegenen atrioventriculären akzessorischen Leitungsbahn (MS) eingeschlossen, die seit 4 Jahren in unserem Elekt...
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Article
Short-coupled variant of torsade de pointes
Presented in this paper were 3 cases of a special kind of polymorphic ventricular tachycardia (VT). The clinical manifestation was recurrent syncope without organic heart disease. The electrocardiogram (ECG) w...