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Article
Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation
Cellular FLICE-inhibitory protein (c-FLIP) is an inhibitor of caspase-8 and is required for macrophage survival. Recent studies have revealed a selective role of caspase-8 in noncanonical IL-1β production that is...
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Article
Open AccessProtogenin prevents premature apoptosis of rostral cephalic neural crest cells by activating the α5β1-integrin
The bones and connective tissues of the murine jaws and skull are partly derived from cephalic neural crest cells (CNCCs). Here, we report that mice deficient of protogenin (Prtg) protein, an immunoglobulin do...