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  1. Article

    Tonicity-responsive enhancer binding protein haplodeficiency attenuates seizure severity and NF-κB-mediated neuroinflammation in kainic acid-induced seizures

    Kainic acid (KA)-induced seizures followed by neuronal death are associated with neuroinflammation and blood–brain barrier (BBB) leakage. Tonicity-responsive enhancer binding protein (TonEBP) is known as a tra...

    H J Shin, H Kim, R W Heo, H J Kim, W S Choi, H M Kwon in Cell Death & Differentiation (2014)

  2. Article

    SIGN-R1, a C-type lectin, enhances apoptotic cell clearance through the complement deposition pathway by interacting with C1q in the spleen

    Complements, such as C1q and C3, and macrophages in the splenic marginal zone (MZMs) play pivotal roles in the efficient uptake and processing of circulating apoptotic cells. SIGN-R1, a C-type lectin that is h...

    M G Prabagar, Y Do, S Ryu, J-Y Park, H-J Choi, W-S Choi in Cell Death & Differentiation (2013)

  3. Article

    Pancreatic β-cell prosurvival effects of the incretin hormones involve post-translational modification of Kv2.1 delayed rectifier channels

    Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are the major incretin hormones that exert insulinotropic and anti-apoptotic actions on pancreatic β-cells. Insulinotropic ac...

    S-J Kim, S B Widenmaier, W S Choi, C Nian, Z Ao, G Warnock in Cell Death & Differentiation (2012)