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  1. Article

    Open Access

    Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

    Patients with autoimmune polyendocrinopathy syndrome type 1 (APS-1) caused by autosomal recessive AIRE deficiency produce autoantibodies that neutralize type I interferons (IFNs)1,2, conferring a predisposition t...

    Tom Le Voyer, Audrey V. Parent, **an Liu, Axel Cederholm, Adrian Gervais in Nature (2023)