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  1. No Access

    Chapter

    What does Evolution Teach us about Nuclear Receptors?

    In this chapter we first summarise the current knowledge about the phylogenetic spectrum of nuclear receptors (NRs). Then, we discuss how studying their diversity can be helpful to make insights about their ev...

    Gabriel Markov, FranÇois Bonneton, Vincent Laudet in Nuclear Receptors (2010)

  2. No Access

    Article

    Mutual repression of transcriptional activation between the ETS-related factor ERG and estrogen receptor

    Transcription factors are known to interact with each other to modulate their transcriptional activity. In this study, we found that the transcriptional activity of human Erg (one of the Ets family-transcripti...

    Virginie Vlaeminck-Guillem, Jean-Marc Vanacker, Alexis Verger, Nathalie Tomavo… in Oncogene (2003)

  3. No Access

    Article

    Molecular phylogeny of the ETS gene family

    We have constructed a molecular phylogeny of the ETS gene family. By distance and parsimony analysis of the ETS conserved domains we show that the family containing so far 29 different genes in vertebrates can...

    Vincent Laudet, Catherine Hänni, Dominique Stéhelin… in Oncogene (1999)

  4. No Access

    Article

    Activation of the thyroid hormone receptor α gene promoter by the orphan nuclear receptor ERRα

    The superfamily of nuclear receptors comprises transcription factors that depend on a ligand for their activity. In addition, the superfamily includes a number of orphan receptors, for which no ligand is known...

    Jean-Marc Vanacker, Edith Bonnelye, Cateline Delmarre, Vincent Laudet in Oncogene (1998)

  5. No Access

    Article

    Rel/NF-κB transcription factors and IκB inhibitors: Evolution from a unique common ancestor

    From the sequences of Rel/NF-κB and IκB proteins, we constructed an alignment of their Rel Homology Domain (RHD) and ankyrin repeat domain. Using this alignment, we performed tree reconstruction with both dist...

    Christelle Huguet, Pascale Crepieux, Vincent Laudet in Oncogene (1997)

  6. No Access

    Chapter

    The c-Ha-ras Oncogene Induces Increased Expression of β-Galactoside α-2,6-Sialyltransferase in Rat Fibroblast (FR3T3) Cells

    Elucidation of the molecular and cellular changes that accompany malignant conversion of normal cell populations is central to the understanding of cancer. Cell surface carbohydrates display structural alterat...

    Nadia Le Marer, Vincent Laudet, Eric C. Svensson… in The Superfamily of ras-Related Genes (1991)