4 Result(s)
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Viktor Petukhov
Life Sciences
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Article
Open AccessdropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments
Recent single-cell RNA-seq protocols based on droplet microfluidics use massively multiplexed barcoding to enable simultaneous measurements of transcriptomes for thousands of individual cells. The increasing c...
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Article
Joint analysis of heterogeneous single-cell RNA-seq dataset collections
Single-cell RNA sequencing is often applied in study designs that include multiple individuals, conditions or tissues. To identify recurrent cell subpopulations in such heterogeneous collections, we developed ...
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Article
Cell segmentation in imaging-based spatial transcriptomics
Single-molecule spatial transcriptomics protocols based on in situ sequencing or multiplexed RNA fluorescent hybridization can reveal detailed tissue organization. However, distinguishing the boundaries of ind...
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Article
Open AccessGene panel selection for targeted spatial transcriptomics
Targeted spatial transcriptomics hold particular promise in analyzing complex tissues. Most such methods, however, measure only a limited panel of transcripts, which need to be selected in advance to inform on...
