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Article
Open AccessApelin promotes blood and lymph vessel formation and the growth of melanoma lung metastasis
Apelin, a ligand of the APJ receptor, is overexpressed in several human cancers and plays an important role in tumor angiogenesis and growth in various experimental systems. We investigated the role of apelin ...
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Article
Open Access3D histopathology of human tumours by fast clearing and ultramicroscopy
Here, we describe a novel approach that allows pathologists to three-dimensionally analyse malignant tissues, including the tumour-host tissue interface. Our visualization technique utilizes a combination of u...
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Article
Open AccessRole of (myo)fibroblasts in the development of vascular and connective tissue structure of the C38 colorectal cancer in mice
It remains unclear if the vascular and connective tissue structures of primary and metastatic tumors are intrinsically determined or whether these characteristics are defined by the host tissue. Therefore we e...