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    Article

    Ramelteon: a review of its therapeutic potential in sleep disorders

    Ramelteon is a tricyclic synthetic analog of melatonin that acts specifically on MT1 and MT2 melatonin receptors. Ramelteon’s half-life is longer than that of melatonin, being metabolized in the body to four main...

    Seithikurippu R. Pandi-Perumal, Venkatramanujam Srinivasan… in Advances in Therapy (2009)

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    Article

    Jet lag, circadian rhythm sleep disturbances, and depression: the role of melatonin and its analogs

    Traveling through several time zones results in a constellation of symptoms known as jet lag. These include reduced alertness, daytime fatigue, loss of appetite, reduced cognitive skills, and disruption of the...

    Venkatramanujam Srinivasan, Jarnail Singh… in Advances in Therapy (2010)