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    Article

    Synthesis of 6-alkyl-4-[5-dialkylaminomethyl-4-(4-methyl-1,3-thiazol-2-yl)-1H-pyrazol-3-yl]-1,3-benzenediols

    6-Alkyl-2-dialkylaminomethyl-7-hydroxy-3-(4-methyl-1,3-thiazol-2-yl)-4H-chromen-4-ones recyclized into 6-alkyl-4-[5-dialkylaminomethyl-4-(4-methyl-1,3-thiazol-2-yl)-1H-pyrazol-3-yl]-1,3-benzenediols under the inf...

    T. V. Shokol, N. V. Gorbulenko, A. V. Turov in Chemistry of Heterocyclic Compounds (2013)

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    Article

    Synthesis of 3-hetaryl-1H-isochromen-1-ones based on 3-(2-bromoacetyl)-1H-isochromen-1-one

    A preparative method was developed for the synthesis of 3-(2-bromoacetyl)-1H-isochromen-1-one. Its heterocyclization to 3-(2-R-thiazol-4-yl)-, (3-quinoxalin-2-yl)-, and 3-(imidazo[1,2-a]pyridin-2-yl)-1H-isochrome...

    O. V. Shablykina, O. V. Shablykin, V. V. Ishchenko in Chemistry of Heterocyclic Compounds (2013)

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    Article

    Synthesis of 6-alkyl-2-dialkylaminomethyl-7-hydroxy-3-(4-methylthiazol-2-yl)-4H-chromen-4-ones

    Amination of 6-alkyl-2-chloromethyl-7-hydroxy-3-(4-methylthiazol-2-yl)-4H-chromen-4-ones by secon-dary cyclic amines gives the corresponding 2-dialkylaminomethyl derivatives.

    T. V. Shokol, N. V. Gorbulenko, A. V. Turov in Chemistry of Heterocyclic Compounds (2012)

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    Article

    Chemistry of 3-hetarylcoumarins 3*. Synthesis and aminomethylation of 7′-hydroxy-3,4′- bicoumarins

    An improved procedure for the synthesis of 7′-hydroxy-3,4′-bicoumarins has been developed. Their 8′-aminomethyl derivatives were obtained by interaction with aminals.

    M. S. Frasinyuk, S. P. Bondarenko, V. P. Khilya in Chemistry of Heterocyclic Compounds (2012)

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    Article

    Features of the α-azolyl-2-hydroxy-acetophenones reaction with chloroacetyl chloride

    T. V. Shokol, N. V. Gorbulenko, V. P. Khilya in Chemistry of Heterocyclic Compounds (2012)

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    Article

    Reduction of 3-(carboxyaryl)isocoumarins with sodium borohydride

    Reduction of 3-(carboxyaryl)isocoumarins with sodium borohydride proceeds with formation of corresponding 3-carboxyaryl-3,4-dihydroisocoumarins or isomeric dihydrophthalides, 3-(2-carb-oxybenzyl)-2-benzofuran-1(3

    V. V. Ishchenko, N. M. Voevoda, O. V. Shablykina in Chemistry of Heterocyclic Compounds (2012)

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    Article

    Formylation of 5-hydroxybenzofuran derivatives and synthesis of furo-[3,2-f]coumarins based on them*

    The formylation of esters of 5-hydroxy-1-benzofuran-3-carboxylic acid has been studied. The interaction of the synthesized aldehydes with esters of β-keto acids and hetarylacetonitriles gave furo[3,2-f]coumarin-1...

    M. S. Frasinyuk, S. P. Bondarenko, O. V. Shablykina in Chemistry of Heterocyclic Compounds (2011)

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    Article

    Synthesis and biological activity of chromones annelated at the C(7)–C(8) bond with heterocycles (review)

    Published data on the synthesis of chromones annelated at the C(7)–C(8) bond with nitrogen-, oxygen-, and sulfur-containing heterocycles of various sizes, including those with two and three heteroatoms, are di...

    O. A. Lozinskii, T. V. Shokol, V. P. Khilya in Chemistry of Heterocyclic Compounds (2011)

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    Article

    Reaction of methyl 3-[(dimethylamino)methylidene]-6-fluoro-4-oxo −3,4-dihydrochroman-2-carboxylate with primary and secondary amines*

    A method was developed for substitution of the dimethylamino group by bioisosteric fragments by the action of various primary and secondary amines on methyl 3-[(dimethylamino)methylidene]-6-fluoro-4-oxo-3,4-di...

    A. I. Kysil, V. S. Moskvina, A. V. Turov in Chemistry of Heterocyclic Compounds (2011)

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    Article

    Synthesis of derivatives of the hydrazones of 5-phenylfuro[3,2-g]chromen-7-ones

    Sulfur- and nitrogen-containing derivatives of 5-phenylfurocoumarins at the exocyclic oxygen atom were synthesized. The reaction of the obtained hydrazones with certain carbonyl compounds was investigated.

    D. P. Ostrovskiy, Ya. L. Garazd, M. M. Garazd in Chemistry of Heterocyclic Compounds (2011)

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    Article

    3-[2(4)-Pyrimidinyl]coumarins and their condensed analogs

    3-Pyrimidinylcoumarins have been synthesized by interacting 2- and 4-pyrimidinylacetonitriles with substituted salicylic aldehydes, but 9-pyrimidinylpyrano[2,3-f]chromene-4,8-diones were obtained with 8-formyl...

    T. V. Shokol, I. Yu. Nestorak, A. V. Turov in Chemistry of Heterocyclic Compounds (2010)

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    Article

    Furyl analogs of α-pyrono[2,3-f]isoflavones with an azole substituent in the α-pyrone nucleus

    The corresponding 9-azolyl-8-imino-4H,8H-pyrano[2,3-f]chromen-4-ones have been synthesized by the condensation of 7-hydroxy-3-(5-methoxycarbonyl-2-methylfuran-3-yl)-8-formylchromones with 2-aza-hetarylacetonitril...

    T. V. Shokol, O. A. Lozinskii, T. M. Tkachuk in Chemistry of Heterocyclic Compounds (2010)

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    Article

    Aminomethylation of 3-aryl-7-hydroxycoumarins

    The reaction of the analogs of natural 3-arylbenzopyran-2-ones with electrophilic reagents of aminal structure was studied. Substituted 8-aminomethyl-3-aryl-7-hydroxycoumarins were synthesized. The optimum con...

    S. P. Bondarenko, M. S. Frasinyuk, V. P. Khilya in Chemistry of Heterocyclic Compounds (2010)

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    Article

    Features of the aminomethylation of 7-hydroxy-4′-fluoroisoflavones with primary amines

    The behavior of 7-hydroxy-4′-fluoroisoflavones under the conditions of the Mannich reaction with primary amines was studied. New 9-alkyl-substituted 3-(4-fluorophenyl)-9,10-dihydro-4H,8H-chromeno-[8,7-e][1,3]o...

    S. P. Bondarenko, M. S. Frasinyuk, V. P. Khilya in Chemistry of Heterocyclic Compounds (2010)

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    Article

    Synthesis and properties of 4-(3-amino-2-benzofuranyl)-coumarins

    The alkylation of o-cyanophenol by 4-chloromethylcoumarins and subsequent intramolecular condensation by the cyano and methylene groups gives substituted 4-(3-amino-2-benzo-furanyl)coumarins. We studied the re...

    M. S. Frasinyuk, S. V. Gorelov, S. P. Bondarenko in Chemistry of Heterocyclic Compounds (2009)

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    Article

    Synthesis of 9-azolyl-3-(4-phenyl-4h-1,2,4-triazol-3-yl)-4h,8h-pyrano-[2,3-f]chromene-4,8-diones

    The reaction of 6-ethyl-8-formyl-7-hydroxy-3-(4-phenyl-4H-1,2,4-triazol-3-yl)chromone with 2-azolyl-acetonitriles gave 8-iminopyrano[2,3-f]chromen-4-ones, whose acid hydrolysis led to pyrano-[2,3-f]chromene-4,8-d...

    T. V. Shokol, O. A. Lozinskii, A. V. Turov in Chemistry of Heterocyclic Compounds (2009)

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    Article

    Convenient method for synthesis of 3-(het)-aryl-8-formyl-7-hydroxy-chromones

    T. V. Shokol, N. V. Gorbulenko, T. M. Tkachuk in Chemistry of Heterocyclic Compounds (2009)

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    Article

    Synthesis and properties of 4-chloromethyl-6-hydroxy-coumarins and 4-(2-benzofuryl)-6-hydroxycoumarins

    New 4-chloromethyl-6-hydroxycoumarins have been obtained by the condensation of hydroquinone derivatives with 4-chloroacetoacetic ester, and have been used for the synthesis of 4-(2-benzofuryl)-6-hydroxycoumar...

    M. S. Frasinyuk, S. P. Bondarenko, V. P. Khilya in Chemistry of Heterocyclic Compounds (2009)

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    Article

    Chemistry of hetero analogs of isoflavones 26. Synthesis of 2-alkyl derivatives of 3-(thiazol-2-yl)-and 3-(benzothiazol-2-yl)chromones

    Treatment of substituted 2-(2,4-dihydroxyphenacyl)thiazole and 2-(2,4-dihydroxyphenacyl)benzothiazole with propionic and isobutyric anhydrides gives the substituted 2-ethyl-and 2-isopropyl-7-acyloxychromones. ...

    M. S. Frasinyuk, V. P. Khilya in Chemistry of Heterocyclic Compounds (2008)

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    Article

    Synthesis of amino acid derivatives of hydrazones and oximes of spirodihydropyranochromen-2-ones

    Sulfur-and nitrogen-containing derivatives of spirodihydropyranochromen-2-ones at the exocyclic oxygen atom have been synthesized. Modification of the oximes and hydrazones of the spiro-substituted pyranocouma...

    M. V. Veselovska, M. M. Garazd, O. S. Ogorodniychuk in Chemistry of Heterocyclic Compounds (2008)

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