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  1. Article

    Open Access

    Phase III trial of postoperative cisplatin, interferon alpha-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma – CapRI: study protocol [ISRCTN62866759]

    After surgical intervention with curative intention in specialised centres the five-year survival of patients with carcinoma of the exocrine pancreas is only 15%. The ESPAC-1 trial showed an increased five-yea...

    HP Knaebel, A Märten, J Schmidt, K Hoffmann, C Seiler, K Lindel… in BMC Cancer (2005)

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  2. Article

    Open Access

    Preclinical evaluation of the antiproliferative potential of STI571 in Hodgkin's disease

    STI571 is a selective tyrosine kinase inhibitor with proven therapeutic potential in malignancies expressing c-kit. A strong c-kit and stem cell factor expression was detected in the Hodgkin and Reed Sternberg ce...

    D Re, C Wickenhauser, T Ahmadi, E Buchdunger, M Kochanek… in British Journal of Cancer (2002)

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  3. No Access

    Book and Conference Proceedings

    Immunosurveillance, Immunodeficiencies and Lymphoproliferations

    Lymphoproliferative Disorders in Congenital and Acquired Immunodeficiencies

    Dr. Med. Stephan H. Oertel… in Recent Results in Cancer Research (2002)

  4. Article

    Open Access

    Loss of heterozygosity in the Hodgkin-Reed Sternberg cell line L1236

    Hodgkin-Reed Sternberg cells are derived from germinal centre B-cells in most cases. Somatic mutations affecting their rearranged immunoglobulin genes were detected, rendering potential functional rearrangemen...

    A Staratschek-Jox, R Kurt Thomas, T Zander, N Massoudi… in British Journal of Cancer (2001)

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  5. No Access

    Article

    A real-time PCR assay for the quantification of residual malignant cells in B cell chronic lymphatic leukemia

    Several new therapeutic approaches for the treatment of monoclonal B cell lymphomas are currently being investigated. In parallel with new therapeutic modalities, more sensitive diagnostic methods are needed. ...

    T Pfitzner, A Engert, H Wittor, T Schinköthe, F Oberhäuser, H Schulz, V Diehl… in Leukemia (2000)

  6. No Access

    Book and Conference Proceedings

    Esophageal Carcinoma

    State of the Art

    Prof. Dr. med. Jochen Lange… in Recent Results in Cancer Research (2000)

  7. No Access

    Book and Conference Proceedings

    Peptides in Oncology III

    Somatostatin and LH-RH Analogues

    Prof. Dr. med Klaus Höffken… in Recent Results in Cancer Research (2000)

  8. No Access

    Book and Conference Proceedings

    Gastrointestinal Lymphoma

    Future Perspectives

    Prof Dr. med Wolfgang Fischbach in Recent Results in Cancer Research (2000)

  9. No Access

    Book and Conference Proceedings

    Lymphatic Metastasis and Sentinel Lymphonodectomy

    … in Recent Results in Cancer Research (2000)

  10. No Access

    Article

    Treatment of refractory Hodgkin's lymphoma patients with an anti-CD25 ricin A-chain immunotoxin

    The anti-CD25 immunotoxin RFT5.dgA was constructed by coupling the monoclonal antibody RFT5 via a sterically hindered disulfide linker to deglycosylated ricin A-chain and was administered to patients with rela...

    R Schnell, E Vitetta, J Schindler, P Borchmann, S Barth, V Ghetie, K Hell… in Leukemia (2000)

  11. No Access

    Article

    Initial (prefibrotic) stages of idiopathic (primary) myelofibrosis (IMF) – a clinicopathological study

    A clinicopathological follow-up study including sequential bone marrow biopsies was performed on 79 patients with idiopathic (primary) myelofibrosis (IMF) to characterize initial (prefibrotic) stages and to el...

    J Thiele, HM Kvasnicka, B Boeltken, R Zankovich, V Diehl, R Fischer in Leukemia (1999)

  12. Article

    Open Access

    An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA’) is a potent immunotoxin against a Hodgkin-derived cell line

    The human CD30 receptor is highly overexpressed on the surface of Hodgkin Reed-Sternberg cells and has been shown to be an excellent target for selective immunotherapy using monoclonal antibody-based agents su...

    A Klimka, S Barth, B Matthey, R C Roovers, H Lemke, H Hansen… in British Journal of Cancer (1999)

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  13. No Access

    Book and Conference Proceedings

    Chemoprevention of Cancer

    A Clinical Update

    Prof. Dr. med. Hans-Jörg Senn… in Recent Results in Cancer Research (1999)

  14. No Access

    Article

    Immunotoxins against the vasculature of human Hodgkin’s lymphoma in SCID mice

    D. Schiefer, R. Schnell, C. Gottstein… in Journal of Cancer Research and Clinical On… (1995)

  15. No Access

    Article

    A phase I clinical trial of an anti-CD25-deglycosylated ricin a-chain immunotoxin (RFT5-SMPT-DGA) in patients with Hodgkin’s lymphoma restistent to conventional therapy

    R. Schnell, A. Radszuhn, M. -T. Hatwig… in Journal of Cancer Research and Clinical On… (1995)

  16. No Access

    Article

    The antiemetic efficacy and safety of granisetron compared with metoclopramide plus dexamethasone in patients receiving fractionated chemotherapy over 5 days

    The antiemetic efficacy and safety of granisetron (40 μg/kg), a selective and potent 5-hydroxytryptamine (serotonin) antagonist, was compared with that of metoclopramide (7 mg/kg) plus dexamethasone (12 mg) in...

    M. Aapro, D. Piguet, K. Giger, J. Bauer… in Journal of Cancer Research and Clinical On… (1993)

  17. No Access

    Article

    Monoclonal antibody FW6 generated against a mucin-carbohydrate of human amniotic fluid recognises a colonic tumour-associated epitope

    Mucus glycoproteins of human amniotic fluid were used to generate a monoclonal antibody (MAb) FW6, which stained the intestine of a 24 week stage fetus. In adults, 76% of colonic adenocarcinomas (13/17) showed...

    M Schwonzen, R Schmits, SE Baldus, M Vierbuchen, F-G Hanisch… in British Journal of Cancer (1992)

  18. No Access

    Article

    Cooperative trials of Hodgkin's lymphoma in the Federal Republic of Germany

    V. Diehl, M. Pfreundschuh, M. Löffler… in Journal of Cancer Research and Clinical On… (1990)

  19. Article

    Morbus Hodgkin in adults: Preliminary results of the HD1, HD2 and HD3 trials

    V. Diehl, M. Pfreundschuh, F. E. Hauser… in Journal of Cancer Research and Clinical On… (1986)

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  20. Article

    Rosette inhibiting factor (RIF) produced by Hodgkin-cell lines

    I. Katay, E. Zittlau, H. Burrichter… in Journal of Cancer Research and Clinical On… (1986)

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