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Article
A real-time PCR assay for the quantification of residual malignant cells in B cell chronic lymphatic leukemia
Several new therapeutic approaches for the treatment of monoclonal B cell lymphomas are currently being investigated. In parallel with new therapeutic modalities, more sensitive diagnostic methods are needed. ...
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Article
Treatment of refractory Hodgkin's lymphoma patients with an anti-CD25 ricin A-chain immunotoxin
The anti-CD25 immunotoxin RFT5.dgA was constructed by coupling the monoclonal antibody RFT5 via a sterically hindered disulfide linker to deglycosylated ricin A-chain and was administered to patients with rela...
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Article
Initial (prefibrotic) stages of idiopathic (primary) myelofibrosis (IMF) – a clinicopathological study
A clinicopathological follow-up study including sequential bone marrow biopsies was performed on 79 patients with idiopathic (primary) myelofibrosis (IMF) to characterize initial (prefibrotic) stages and to el...
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Article
Immunotoxins against the vasculature of human Hodgkin’s lymphoma in SCID mice
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Article
A phase I clinical trial of an anti-CD25-deglycosylated ricin a-chain immunotoxin (RFT5-SMPT-DGA) in patients with Hodgkin’s lymphoma restistent to conventional therapy
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Article
The antiemetic efficacy and safety of granisetron compared with metoclopramide plus dexamethasone in patients receiving fractionated chemotherapy over 5 days
The antiemetic efficacy and safety of granisetron (40 μg/kg), a selective and potent 5-hydroxytryptamine (serotonin) antagonist, was compared with that of metoclopramide (7 mg/kg) plus dexamethasone (12 mg) in...
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Article
Cooperative trials of Hodgkin's lymphoma in the Federal Republic of Germany
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Article
Morbus Hodgkin in adults: Preliminary results of the HD1, HD2 and HD3 trials
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Article
Rosette inhibiting factor (RIF) produced by Hodgkin-cell lines
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Article
Phase-I-trial of tumor-necrosis-factor in patients with malignant disease
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Article
Homogeneous growth of tumor cell colonies in agar containing glas capillaries
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Article
Immunohistological analysis of Hodgkin's and Sternberg-Reed cells: Detection of a new antigen and evidence for selective IgG uptake in the absence of B cell, T cell and histiocytic markers
To help clarify the origin and nature of Hodgkin's (H) and Sternberg-Reed (SR) cells, three different sets of experiments were performed. First, it was shown that cytoplasmic γ, ϰ, and λ occur not only in H an...
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Article
Hodgkin's disease: Establishment and characterization of four in vitro cell lines
Four in vitro cell lines (L 428, L 439, L 538, and L 540) were established from different materials of three patients with Hodgkin's disease: pleural effusions, peripheral blood, and bone marrow. The histologi...