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  1. Article

    Open Access

    Alterations in leukocyte transcriptional control pathway activity associated with major depressive disorder and antidepressant treatment

    Major depressive disorder (MDD) is associated with a significantly elevated risk of develo** serious medical illnesses such as cardiovascular disease, immune impairments, infection, dementia and premature de...

    S H Mellon, O M Wolkowitz, M D Schonemann, E S Epel, R Rosser in Translational Psychiatry (2016)

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    Article

    Genome-wide association study of Tourette's syndrome

    Tourette's syndrome (TS) is a developmental disorder that has one of the highest familial recurrence rates among neuropsychiatric diseases with complex inheritance. However, the identification of definitive TS...

    J M Scharf, D Yu, C A Mathews, B M Neale, S E Stewart in Molecular Psychiatry (2013)

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    Article

    Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response

    Telomeres are DNA-protein complexes that cap linear DNA strands, protecting DNA from damage. When telomeres critically shorten, cells become susceptible to senescence and apoptosis. Telomerase, a cellular ribo...

    O M Wolkowitz, S H Mellon, E S Epel, J Lin, V I Reus, R Rosser in Molecular Psychiatry (2012)