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Article
Treatment of Tourette Syndrome with Delta-9-Tetrahydrocannabinol (Δ9-THC): No Influence on Neuropsychological Performance
Previous studies provide evidence that marijuana (Cannabis sativa) and delta-9-tetrahydrocannabinol (Δ9-THC), the major psychoactive ingredient of marijuana, respectively, are effective in the treatment of tics a...
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Article
Open AccessN-terminal fragment of B-type natriuretic peptide (NT-proBNP), a marker of cardiac safety during antipsychotic treatment
The potential cardiotoxicity of antipsychotic drugs is well known. The N-terminal fragment of B-type natriuretic peptide (NT-proBNP) is considered to be a possible biomarker in clinical practice for the diagno...
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Article
Open AccessThe cross-sectional GRAS sample: A comprehensive phenotypical data collection of schizophrenic patients
Schizophrenia is the collective term for an exclusively clinically diagnosed, heterogeneous group of mental disorders with still obscure biological roots. Based on the assumption that valuable information abou...
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Article
Open AccessMotives for khat use and abstinence in Yemen - a gender perspective
Khat consumption is widespread in Yemeni society and causes problems both in economic development and public health. Preventive measures have been largely unsuccessful and the cultivation continues to prolifer...
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Article
Open AccessImproving Prevention Compliance through Appropriate Incentives: Theoretical Modelling and Empirical Evidence
This paper explores the effects of insurance parameters and complementary information environment on the patient’s primary prevention activity. The theoretical model is based on a principal-agent setting in wh...
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Article
Open AccessDiagnostic value and clinical laboratory associations of antibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in a Caucasian cohort with systemic lupus erythematosus
In this study, we sought to determine the diagnostic value and clinical laboratory associations of autoantibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in systemic...
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Article
Open AccessDelayed contrast-enhanced MRI of the coronary artery wall in patients with Takayasu's arteritis: initial experience and comparison to patients with stable coronary artery disease
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Article
Open AccessReporting heterogeneity in self-assessed health among elderly Europeans
Self-assessed health (SAH) is a frequently used measure of individuals’ health status. It is also prone to reporting heterogeneity. To control for reporting heterogeneity objective measures of true health need...
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Article
Open AccessGPCC's new land surface precipitation climatology based on quality-controlled in situ data and its role in quantifying the global water cycle
In 1989, the need for reliable gridded land surface precipitation data sets, in view of the large uncertainties in the assessment of the global energy and water cycle, has led to the establishment of the Globa...
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Article
Open AccessDifferential roles of hypoxia and innate immunity in juvenile and adult dermatomyositis
Dermatomyositis (DM) can occur in both adults and juveniles with considerable clinical differences. The links between immune-mediated mechanisms and vasculopathy with respect to development of perifascicular p...
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Article
Obituary for Professor Hinderk Meiners Emrich, MD PhD
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Article
Open AccessEpidemiology and cost of seasonal influenza in Germany - a claims data analysis
Seasonal influenza contributes substantially to the burden of communicable diseases in Europe, especially among paediatric populations and the elderly. The aim of the present study was to estimate the incidenc...
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Article
Open AccessEvaluating the GPCC Full Data Daily Analysis Version 2018 through ETCCDI indices and comparison with station observations over mainland of China
The new 1° × 1° resolution global Full Data Daily Analysis Version 2018 published by the Global Precipitation Climatology Centre (GPCC) of Deutscher Wetterdienst was compared with an analysis of the measuremen...
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Article
Open AccessIntensity dependent effect of cognitive training on motor cortical plasticity and cognitive performance in humans
Intervention-induced neuroplastic changes within the motor or cognitive system have been shown in the human brain. While cognitive and motor brain areas are densely interconnected, it is unclear whether this i...
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Article
Open AccessDo discontinuities in marginal reimbursement affect inpatient psychiatric care in Germany?
This paper examines the behaviour of mental health care providers in response to marginal payment incentives induced by a discontinuous per diem reimbursement schedule with varying tariff rates over the length...
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Article
Open AccessThiamazol-induzierte Arthritis
Wir berichten über den Fall eines 42-jährigen Patienten mit akuter asymmetrischer Polyarthritis der großen und mittelgroßen Gelenke sowie Fieber und erhöhten serologischen Entzündungszeichen. Die Symptomatik b...
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Article
Open AccessSystemic sclerosis-associated myositis features minimal inflammation and characteristic capillary pathology
Systemic sclerosis represents a chronic connective tissue disease featuring fibrosis, vasculopathy and autoimmunity, affecting skin, multiple internal organs, and skeletal muscles. The vasculopathy is consider...
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Article
Open AccessTreatment-Related Healthcare Costs of Metastatic Castration-Resistant Prostate Cancer in Germany: A Claims Data Study
Treatments for patients with metastatic castration-resistant prostate cancer (mCRPC) have expanded rapidly. They include the chemotherapies docetaxel and cabazitaxel, hormonal drugs abiraterone and enzalutamid...
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Article
Open AccessThe impact of nurse staffing levels on nursing-sensitive patient outcomes: a multilevel regression approach
The goal of this study is to provide empirical evidence of the impact of nurse staffing levels on seven nursing-sensitive patient outcomes (NSPOs) at the hospital unit level. Combining a very large set of clai...
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Article
Open AccessImproving the continuity and coordination of ambulatory care through feedback and facilitated dialogue—a study protocol for a cluster-randomised trial to evaluate the ACD study (Accountable Care in Germany)
Patients in Germany are free to seek care from any office-based physician and can always ask for multiple opinions on a diagnosis or treatment. The high density of physicians and the freedom to choose among th...
