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Chapter
Angiogenic Gene Therapy for the Treatment of Retinopathies
In the past decade, advances in vector design and delivery have helped guide gene therapy technologies from the laboratory to clinical trials. These technologies are poised to tackle a key problem in opthalmol...
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Protocol
Retinal Tissue
Mutations within genes that are specifically expressed within the retina and/or the retinal pigment epithelium (RPE) are associated with the majority of inherited retinal degenerations (1). Retinal degenerative d...
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Protocol
Corneal Cells
A mammalian cornea can be maintained in vitro for days (1,2), allowing ex vivo transduction of this tissue prior to transplantation (3,4). Ex vivo transduction of the cornea is useful for studying the efficacy of...