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  1. Article

    Open Access

    The Aldose Reductase Inhibitor Epalrestat Maintains Blood–Brain Barrier Integrity by Enhancing Endothelial Cell Function during Cerebral Ischemia

    Excessive activation of aldose reductase (AR) in the brain is a risk factor for aggravating cerebral ischemia injury. Epalrestat is the only AR inhibitor with proven safety and efficacy, which is used in the c...

    Tongshuai Zhang, **rong Wu, **nmin Yao, Yao Zhang, Yue Wang… in Molecular Neurobiology (2023)

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  2. Article

    Open Access

    Accumulation of natural killer cells in ischemic brain tissues and the chemotactic effect of IP-10

    Stroke is accompanied by a distinguished inflammatory reaction that is initiated by the infiltration of immunocytes, expression of cytokines, and other inflammatory mediators. As natural killer cells (NK cells...

    Yao Zhang, Zhongming Gao, Dandan Wang, Tongshuai Zhang… in Journal of Neuroinflammation (2014)

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