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  1. Article

    Open Access

    MGMT gene promoter methylation by pyrosequencing method correlates volumetric response and neurological status in IDH wild-type glioblastomas

    Although the usefulness of O6-methylguanine DNA methyltransferase (MGMT) promoter methylation analysis for predicting response to chemoradiotherapy and the prognosis of patients with glioblastoma has been widely ...

    Tomohiro Hosoya, Masamichi Takahashi, Mai Honda-Kitahara in Journal of Neuro-Oncology (2022)

  2. No Access

    Article

    Intravenous Alteplase is Associated with First Pass Effect in Stent-retriever but not ADAPT Thrombectomy

    To investigate the effect of alteplase, either combined with stent-retriever thrombectomy or a direct aspiration first pass technique (ADAPT), in patients with large-vessel occlusion stroke.

    Keigo Shigeta, Kentaro Suzuki, Yuji Matsumaru, Masataka Takeuchi in Clinical Neuroradiology (2022)

  3. Article

    Open Access

    Can the Japanese National Clinical Database risk calculator predict long-term survival of patients who undergo palliative segmentectomy for primary lung cancer?

    Selection criteria for palliative limited surgery in patients with non-small cell lung cancer (NSCLC) can vary by institution or surgeon. We retrospectively reviewed outcomes of poor-risk patients who underwen...

    Tomoyuki Nakano, Hiroyoshi Tsubochi in General Thoracic and Cardiovascular Surgery (2021)

  4. No Access

    Article

    Efficacy and Safety of Mechanical Thrombectomy for Occlusion of the Second Segment of the Middle Cerebral Artery

    The efficacy of mechanical thrombectomy in the treatment of occlusions of the second segment of the middle cerebral artery (M2) has not been firmly established.

    Tomoyuki Nakano, Keigo Shigeta, Takahiro Ota, Tatsuo Amano in Clinical Neuroradiology (2020)

  5. Article

    Open Access

    Pericardial fat pad plombage for pulmonary cavity causing massive air leakage

    Secondary pneumothorax after chemotherapy for a malignant pulmonary tumor is a complication from a large cavity causing refractory pneumothorax.

    Tomoyuki Nakano, Hiroyoshi Tsubochi, Kentaro Minegishi in Surgical Case Reports (2020)

  6. Article

    Open Access

    Composite resection of the left upper lobe and superior segment (S6) of the lower lobe for lung cancer with a mediastinal lingular and basal pulmonary artery

    Preoperative evaluation and awareness of anatomical variations in the pulmonary vessel is essential for a secure pulmonary resection. We herein present a patient who underwent complex pulmonary resection for l...

    Tomoyuki Nakano, Shigemi Ishikawa, Yasunori Sohara, Shunsuke Endo in Surgical Case Reports (2018)

  7. No Access

    Article

    Roles of lipid-modulating enzymes diacylglycerol kinase and cyclooxygenase under pathophysiological conditions

    Lipid not only represents a constituent of the plasma membrane, but also plays a pivotal role in intracellular signaling. Lipid-mediated signaling system is strictly regulated by several enzymes, which act at...

    Tomoyuki Nakano in Anatomical Science International (2015)

  8. No Access

    Article

    Extended sleeve lobectomy for interlobar lymph node metastasis invading the bronchus from peripheral lung cancer

    Although extended sleeve lobectomy has been used as an alternative to pneumonectomy for the treatment of centrally located lung cancer, the validity of this surgical procedure is unclear in patients with perip...

    Hiroyoshi Tsubochi, Yoshihiko Kanai in General Thoracic and Cardiovascular Surgery (2011)

  9. No Access

    Article

    Thymic clear cell carcinoma

    We report a 42-year-old man with a rare thymic clear cell carcinoma. Marked nodal metastases involved right hilar, mediastinal, and left supraclavicular regions. Complete resection including thymothymectomy, c...

    Tomoyuki Nakano, Shunsuke Endo in General Thoracic and Cardiovascular Surgery (2010)

  10. No Access

    Article

    Descending necrotizing mediastinitis secondary to retropharyngeal abscess without cervical spread

    Cervical infections can cause neck phlegmonosa and occasionally develop lethal mediastinitis. We report a 52-year-old man with a retropharyngeal abscess causing descending mediastinis without cervical spread. ...

    Shunsuke Endo, Hiroyoshi Tsubochi in General Thoracic and Cardiovascular Surgery (2008)