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Safety and tolerability of IgPro10 in Japanese primary immunodeficiency patients: a registrational study

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  1. Article

    Open Access

    Intravenous abatacept in Japanese patients with polyarticular-course juvenile idiopathic arthritis: results from a phase III open-label study

    To investigate efficacy and safety of intravenous abatacept in Japanese patients with active polyarticular-course juvenile idiopathic arthritis (pJIA).

    Ryoki Hara, Hiroaki Umebayashi, Syuji Takei, Nami Okamoto in Pediatric Rheumatology (2019)

  2. Article

    Open Access

    Identification of candidate diagnostic serum biomarkers for Kawasaki disease using proteomic analysis

    Kawasaki disease (KD) is a systemic vasculitis and childhood febrile disease that can lead to cardiovascular complications. The diagnosis of KD depends on its clinical features, and thus it is sometimes diffic...

    Yayoi Kimura, Masakatsu Yanagimachi, Yoko Ino, Mao Aketagawa in Scientific Reports (2017)

  3. Article

    Open Access

    Update of the japanese national registry of pediatric rheumatic disease

    Ken-Ichi Yamagchi, Yasuhito Nerome, Tomoyuki Imagawa in Pediatric Rheumatology (2014)

  4. Article

    Open Access

    Efficacy, pharmacokinetics, and safety of adalimumab in pediatric patients with juvenile idiopathic arthritis in Japan

    The objective of this study was to evaluate the efficacy, pharmacokinetics, and safety of adalimumab in patients with polyarticular juvenile idiopathic arthritis (JIA) in Japan. Patients aged 4 to 17 years wer...

    Tomoyuki Imagawa, Syuji Takei, Hiroaki Umebayashi in Clinical Rheumatology (2012)

  5. Article

    Open Access

    Tocilizumab-effects on growth impairment in systemic juvenile idiopathic arthritis

    Takako Miyamae, Tomo Nozawa, Masako Kikuchi, Toshitaka Kizawa in Pediatric Rheumatology (2011)

  6. Article

    Open Access

    Correlation between clinical indices and findings of joint ultrasonography in juvenile idiopathic arthritis with adalimumab therapy

    Ryoki Hara, Tomoyuki Imagawa, Takuma Hara, Masako Kikuchi in Pediatric Rheumatology (2011)

  7. Article

    Open Access

    Effect of anakinra on arthropathy in CINCA/NOMID syndrome

    CINCA/NOMID is an autoinflammatory disorder characterized by the triad of neonatal onset of cutaneous symptoms, chronic meningitis, and recurrent fever and it presents with distinctive osteoarthropathy, synovi...

    Takako Miyamae, Yutaka Inaba, Gen Nishimura, Masako Kikuchi in Pediatric Rheumatology (2010)

  8. Article

    Open Access

    Efficacy of thalidomide in a girl with inflammatory calcinosis, a severe complication of juvenile dermatomyositis

    We report a 14-year-old girl with juvenile dermatomyositis (JDM) complicated by severe inflammatory calcinosis successfully treated with thalidomide. She was diagnosed as JDM when she was 4 years old after a f...

    Takako Miyamae, Fumie Sano, Remi Ozawa, Tomoyuki Imagawa in Pediatric Rheumatology (2010)

  9. Article

    Open Access

    Methotrexate for the treatment of juvenile idiopathic arthritis: process to approval for JIA indication in Japan

    Methotrexate (MTX), the primary treatment for the articular-type juvenile idiopathic arthritis (JIA), is effective and brings about radiological improvement. Patient compliance is good, and it is recognized th...

    Masaaki Mori, Takuya Naruto, Tomoyuki Imagawa, Takuji Murata in Modern Rheumatology (2009)

  10. Article

    Cross-cultural adaptation and validation of the Japanese version of the Childhood Health Assessment Questionnaire (CHAQ)

    Takako Miyamae, Akinobu Nemoto, Tomoyuki Imagawa, Kenji Ohshige in Modern Rheumatology (2008)

  11. Article

    Open Access

    Serum protein profile in systemic-onset juvenile idiopathic arthritis differentiates response versus nonresponse to therapy

    Systemic-onset juvenile idiopathic arthritis (SJIA) is a disease of unknown etiology with an unpredictable response to treatment. We examined two groups of patients to determine whether there are serum protein...

    Takako Miyamae, David E Malehorn, Bonnie Lemster in Arthritis Research & Therapy (2005)

  12. Article

    Two-generation Kawasaki Disease: Mother and Daugher

    Evidence that the incidence of Kawasaki disease (KD) in siblings is much higher than general incidence, indicates that genetic factors may contribute to the susceptibility. We report a girl with KD whose mothe...

    Masaaki Mori, Rumiko Kurosawa, Takako Miyamae, Tomoyuki Imagawa in Pediatric Research (2003)

  13. Article

    Effect of Plasma Exchange in Kawasaki Disease Refractory to High Dose Intravenous Gammaglobulin Therapy

    Background: In Kawasaki disease (KD), administration of intravenous gammma-globulin (IVGG) reduced frequency of coronary artery lesion (CAL) from 25% to 8%. However, approximately 500 children still develop CAL e...

    Takako Miyamae, Tomoyuki Imagawa, Shuichi Ito, Masaaki Mori in Pediatric Research (2003)

  14. Article

    Hypercytokinemia is Not Originated from Peripheral Mononuclear Cells at Acute Phase of Kawasaki Disease

    Immune activation and generalized vasculitis are two central features of Kawasaki disease (KD). Recent observations indicated that serum levels of cytokines including interferon(INF)- γ, tumor necrosis factor ...

    Naoki Kobayashi, Masaaki Mori, Yoshinori Kobayashi, Takako Miyamae in Pediatric Research (2003)