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Open AccessIntravenous abatacept in Japanese patients with polyarticular-course juvenile idiopathic arthritis: results from a phase III open-label study
To investigate efficacy and safety of intravenous abatacept in Japanese patients with active polyarticular-course juvenile idiopathic arthritis (pJIA).
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Open AccessUpdate of the japanese national registry of pediatric rheumatic disease
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Open AccessTocilizumab-effects on growth impairment in systemic juvenile idiopathic arthritis
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Open AccessCorrelation between clinical indices and findings of joint ultrasonography in juvenile idiopathic arthritis with adalimumab therapy
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PET assessment of disease activity in children with juvenile idiopathic arthritis
The degree of 18-fluorodeoxyglucose (FDG) uptake is previously reported to correlate with physical examination and laboratory tests for evaluating disease activity in patients with rheumatoid arthritis. The cl...
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Open AccessEffect of anakinra on arthropathy in CINCA/NOMID syndrome
CINCA/NOMID is an autoinflammatory disorder characterized by the triad of neonatal onset of cutaneous symptoms, chronic meningitis, and recurrent fever and it presents with distinctive osteoarthropathy, synovi...
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Open AccessEfficacy of thalidomide in a girl with inflammatory calcinosis, a severe complication of juvenile dermatomyositis
We report a 14-year-old girl with juvenile dermatomyositis (JDM) complicated by severe inflammatory calcinosis successfully treated with thalidomide. She was diagnosed as JDM when she was 4 years old after a f...
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Mizoribine for renal sarcoidosis: effective steroid tapering and prevention of recurrence
Sarcoidosis is a systemic disease of unknown etiology that is characterized by chronic non-caseating granulomatous inflammation with tissue destruction. It is an uncommon disease in children, and renal sarcoid...
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Plasma exchange for refractory Kawasaki disease
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Two-generation Kawasaki Disease: Mother and Daugher
Evidence that the incidence of Kawasaki disease (KD) in siblings is much higher than general incidence, indicates that genetic factors may contribute to the susceptibility. We report a girl with KD whose mothe...
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Effect of Plasma Exchange in Kawasaki Disease Refractory to High Dose Intravenous Gammaglobulin Therapy
Background: In Kawasaki disease (KD), administration of intravenous gammma-globulin (IVGG) reduced frequency of coronary artery lesion (CAL) from 25% to 8%. However, approximately 500 children still develop CAL e...
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Hypercytokinemia is Not Originated from Peripheral Mononuclear Cells at Acute Phase of Kawasaki Disease
Immune activation and generalized vasculitis are two central features of Kawasaki disease (KD). Recent observations indicated that serum levels of cytokines including interferon(INF)- γ, tumor necrosis factor ...