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  1. Article

    Open Access

    Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia

    KMT2A-rearranged infant acute lymphoblastic leukemia (ALL) represents the most refractory type of childhood leukemia. To uncover the molecular heterogeneity of this disease, we perform RNA sequencing, methylation...

    Tomoya Isobe, Masatoshi Takagi, Aiko Sato-Otsubo, Akira Nishimura… in Nature Communications (2022)

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