5 Result(s)

Article

Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages

Katherine Sturgess, Eliza Yankova, M. S. Vijayabaskar, Tomoya Isobe… in Leukemia (2023)

Article

Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism

Neuroblastomas require novel therapies that are based on the exploitation of their biological mechanism. To address this need, we analyzed the DNA methylation and expression datasets of neuroblastomas, extract...

Kentaro Watanabe, Shunsuke Kimura, Masafumi Seki, Tomoya Isobe, Yasuo Kubota… in Oncogene (2022)

Article

Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets

Although hepatoblastoma is the most common pediatric liver cancer, its genetic heterogeneity and therapeutic targets are not well elucidated. Therefore, we conducted a multiomics analysis, including mutatome, ...

Masahiro Sekiguchi, Masafumi Seki, Tomoko Kawai, Kenichi Yoshida… in npj Precision Oncology (2020)