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    Design of fast proteolysis-based signaling and logic circuits in mammalian cells

    Cellular signal transduction is predominantly based on protein interactions and their post-translational modifications, which enable a fast response to input signals. Owing to difficulties in designing new uni...

    Tina Fink, Jan Lonzarić, Arne Praznik, Tjaša Plaper… in Nature Chemical Biology (2019)