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Article
Open AccessRegulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stress
Integrins are closely related to mechanical conduction and play a crucial role in the osteogenesis of human mesenchymal stem cells. Here we wondered whether tensile stress could influence cell differentiation ...
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Article
Roles of oncogenes in esophageal squamous cell carcinoma and their therapeutic potentials
Esophageal squamous cell carcinoma (ESCC) is the most common type of esophageal cancer (EC) in Asia. It is a malignant digestive tract tumor with abundant gene mutations. Due to the lack of specific diagnostic...
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Article
Open AccessPhospholipase C delta 1 inhibits WNT/β‐catenin and EGFR-FAK-ERK signaling and is disrupted by promoter CpG methylation in renal cell carcinoma
PLCD1, located at 3p22, encodes an enzyme that mediates cellular metabolism and homeostasis, intracellular signal transduction and movement. PLCD1 plays a pivotal role in tumor suppression of several types of can...
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Article
Open AccessCompositional changes and ecological characteristics of earthworm mucus under different electrical stimuli
Earthworm mucus is rich in nutrients that can initiate the mineralization and humification of organic matter and is of great importance for contaminated soil remediation and sludge reutilization. In this study...
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Article
RETRACTED ARTICLE: Optimization effect of ecological restoration based on high-resolution remote sensing images in the ecological construction of soil and water conservation
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Article
Open AccessThe role of serum amyloid A1 in the adipogenic differentiation of human adipose-derived stem cells basing on single-cell RNA sequencing analysis
Adipose-derived stem cells (ASCs) are obtained from a variety of sources in vivo where they present in large quantities. These cells are suitable for use in autologous transplantation and the construction of t...
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Article
Open AccessRegulation of the integrin αVβ3- actin filaments axis in early osteogenesis of human fibroblasts under cyclic tensile stress
Integrins play a prominent role in osteogenic differentiation by transmitting both mechanical and chemical signals. Integrin expression is closely associated with tensile stress, which has a positive effect on...
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Article
Open AccessContribution of root respiration to total soil respiration during non-growing season in mine reclaimed soil with different covering-soil thicknesses
An accurate assessment of root respiration in mine reclaimed soil is important for effectively evaluating mining area ecosystems. This study investigated dynamic changes in root respiration and the contributio...
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Article
Open AccessActin polymerization state regulates osteogenic differentiation in human adipose-derived stem cells
Actin is an essential cellular protein that assembles into microfilaments and regulates numerous processes such as cell migration, maintenance of cell shape, and material transport.
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Article
A Comparative Study on Sorption Characteristics by Corn Stalk Pith Using Green Modification with Different Polycarboxylic Acids
In this study, an efficient and economical modification with low chemical concentration process was used for preparing biosorbent. Corn stalk pith (CP) was esterified with different polycarboxylic (tartaric, c...
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Article
Open AccessSynthesis of aligned porous polyethylene glycol/silk fibroin/hydroxyapatite scaffolds for osteoinduction in bone tissue engineering
The physical factors of the extracellular matrix have a profound influence on the differentiation behavior of mesenchymal stem cells. In this study, the effect of the biophysical microenvironment on rat bone m...
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Article
Open AccessA glance on the role of actin in osteogenic and adipogenic differentiation of mesenchymal stem cells
Mesenchymal stem cells (MSCs) have the capacity to differentiate into multiple lineages including osteogenic and adipogenic lineages. An increasing number of studies have indicated that lineage commitment by M...
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Article
Influence of coal gangue aided phytostabilization on metal availability and mobility in copper mine tailings
Copper mine tailings without proper remediation deposited permanently in tailings ponds would pose adverse impacts to the environment. Coal gangue, with high nutrients, used in infertile soil, is investigated ...
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Article
Open AccessCross-talk between microtubules and the linker of nucleoskeleton complex plays a critical role in the adipogenesis of human adipose-derived stem cells
Adipose-derived stem cells (ASCs) that show multidifferentiation and anti-immune rejection capacities have been widely used in plastic and reconstructive surgery. Previous studies have indicated that mechanica...
