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  1. Article

    Open Access

    Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma

    SIRT1 is a member of the mammalian sirtuin family with the ability to deacetylate histone and nonhistone proteins. The correlation between SIRT1 expression and tumor metastasis in several types of cancer has a...

    Chong Hao, Peng-** Zhu, Xue Yang, Zhi-Peng Han, **g-Hua Jiang, Chen Zong… in BMC Cancer (2014)

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  2. Article

    Preparation, characterization and in vivo evaluation of bergenin-phospholipid complex

    To prepare a bergenin-phospholipid complex (BPC) to increase oral bioavailability of the drug.

    Xuan Qin, Yang Yang, Ting-ting Fan, Tao Gong, **ao-ning Zhang… in Acta Pharmacologica Sinica (2010)

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  3. No Access

    Article

    The pharmacokinetics of JS-38, a novel antineoplastic drug, in rats

    To evaluate the pre-clinical pharmacokinetics of JS-38(C22H14O4N2S2F6 MW: 548), a study was conducted in Wistar rats (3 ♀, 2 ♂: 200∼250 g about 6 or 7 months). The concentration-time curve of JS-38 in rats demons...

    Hong Zhang, Yu Fang, Ying Li, Ting-Ting Fan… in European Journal of Drug Metabolism and Ph… (2008)