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Open AccessStrain-level profiling of viable microbial community by selective single-cell genome sequencing
Culture-independent analysis with high-throughput sequencing has been widely used to characterize bacterial communities. However, signals derived from non-viable bacteria and non-cell DNA may inhibit its chara...
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Article
Open AccessRecovery of strain-resolved genomes from human microbiome through an integration framework of single-cell genomics and metagenomics
Obtaining high-quality (HQ) reference genomes from microbial communities is crucial for understanding the phylogeny and function of uncultured microbes in complex microbial ecosystems. Despite improvements in ...