4,387 Result(s)
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Open AccessHigh-density vertical sidewall MoS2 transistors through T-shape vertical lamination
Vertical transistors, in which the source and drain are aligned vertically and the current flow is normal to the wafer surface, have attracted considerable attention recently. However, the realization of high-...
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Open AccessTunable quantum emitters on large-scale foundry silicon photonics
Controlling large-scale many-body quantum systems at the level of single photons and single atomic systems is a central goal in quantum information science and technology. Intensive research and development ha...
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Open AccessDesign of 3D printing osteotomy block for foot based on triply periodic minimal surface
The ankle joint, which connects the lower limbs and the sole of the foot, is prone to sprain during walking and sports, which leads to ankle arthritis. Supratroleolar osteotomy is an ankle preserving operation...
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Open AccessPlasma metabolomics reveals the shared and distinct metabolic disturbances associated with cardiovascular events in coronary artery disease
Risk prediction for subsequent cardiovascular events remains an unmet clinical issue in patients with coronary artery disease. We aimed to investigate prognostic metabolic biomarkers by considering both shared...
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Open AccessPerturbation of METTL1-mediated tRNA N7- methylguanosine modification induces senescence and aging
Cellular senescence is characterized by a decrease in protein synthesis, although the underlying processes are mostly unclear. Chemical modifications to transfer RNAs (tRNAs) frequently influence tRNA activity...
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Open AccessPreferential evaluation of coal filling mining scheme under building pressure based on improved grey target decision-making model of game theory
The problem of coal compression under buildings is common in underground mining of coal mines in China. The selection of traditional mining programme is subjective and lacks scientific rationality. In order to...
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Open AccessDonor-acceptor bulk-heterojunction sensitizer for efficient solid-state infrared-to-visible photon up-conversion
Solid-state infrared-to-visible photon up-conversion is important for spectral-tailoring applications. However, existing up-conversion systems not only suffer from low efficiencies and a need for high excitati...
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Open AccessInhibition of topoisomerase 2 catalytic activity impacts the integrity of heterochromatin and repetitive DNA and leads to interlinks between clustered repeats
DNA replication and transcription generate DNA supercoiling, which can cause topological stress and intertwining of daughter chromatin fibers, posing challenges to the completion of DNA replication and chromos...
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Open AccessGenetically encoded Nδ-vinyl histidine for the evolution of enzyme catalytic center
Genetic code expansion has emerged as a powerful tool for precisely introducing unnatural chemical structures into proteins to improve their catalytic functions. Given the high catalytic propensity of histidin...
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Open AccessHybrid ant colony-based inter-cluster routing protocol for FANET
This study addresses the challenges in large-scale unmanned aerial vehicle (UAV) clusters, specifically the scalability issues and limitations of using reactive routing protocols for inter-cluster routing. The...
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Open AccessStudy on the failure mechanism of high-temperature granite under two cooling modes
In the geothermal development of hot dry rock (HDR), both the drilling of the wellbore and the heat exchange of the heat reservoir involve the effects of different cold and hot conditions on the high-temperatu...
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Open AccessReappropriating the communal past: lineage tradition revival as a way of constructing collective identity in Huizhou, China
This article discusses the reappropriation and redefinition of heritage and tradition as a process of purposeful and selective value extraction by various groups at the local level in Huizhou, China, based on ...
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Open AccessReformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation
Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this. Here, we reformu...
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Open AccessComprehensive application of AI algorithms with TCR NGS data for glioma diagnosis
T-cell receptor (TCR) detection can examine the extent of T-cell immune responses. Therefore, the article analyzed characteristic data of glioma obtained by DNA-based TCR high-throughput sequencing, to predict...
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Open AccessHighly efficient recycling of polyester wastes to diols using Ru and Mo dual-atom catalyst
The chemical recycling of polyester wastes is of great significance for sustainable development, which also provides an opportunity to access various oxygen-containing chemicals, but generally suffers from low...
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Open AccessAuthor Correction: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice
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3D printable elastomers with exceptional strength and toughness
Three-dimensional (3D) printing has emerged as an attractive manufacturing technique because of its exceptional freedom in accessing geometrically complex customizable products. Its potential for mass manufact...
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Open AccessSpeculative culture and corporate high-quality development in China: mediating effect of corporate innovation
This paper associates the speculative culture with the corporate total factor productivity (TFP), aiming to explore the influence of speculative culture on corporate high-quality development. The results revea...
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Open AccessMagnetic excitations in strained infinite-layer nickelate PrNiO2 films
Strongly correlated materials respond sensitively to external perturbations such as strain, pressure, and do**. In the recently discovered superconducting infinite-layer nickelates, the superconducting trans...
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A µ-opioid receptor modulator that works cooperatively with naloxone
The µ-opioid receptor (µOR) is a well-established target for analgesia1, yet conventional opioid receptor agonists cause serious adverse effects, notably addiction and respiratory depression. These factors have c...