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Article
Open AccessNew mouse genetic model of breast cancer from IKKα defects in dendritic cells revealed by single-cell RNA sequencing
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Article
Open AccessHOXC11 drives lung adenocarcinoma progression through transcriptional regulation of SPHK1
Lung adenocarcinoma (LUAD) is a fatal threat to human health, while the mechanism remains unclear, and the therapy brings limited therapeutic effects. Transcription factor Homeobox C11 (HOXC11) was previously ...
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Protocol
ChIP and ChIRP Assays in Ferroptosis
Ferroptosis is characterized by the accumulation of lipid peroxidation driven by iron. As a regulated cell death, ferroptosis plays a critical role in various diseases and exhibits great therapeutic potentials...
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Chapter
Targeting Epigenetic Regulation of Ferroptosis in Cancer Therapy
Ferroptosis is a regulated form of cell death characterized by iron-catalyzed and reactive oxygen species (ROS)-mediated lipid peroxidation. It plays a crucial role in tumorigenesis, tumor progression, and can...