61 Result(s)
within
Takaaki Abe
English
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Article
Patent package structures and sharing rules for royalty revenue
The role of patent pools—one-stop systems that gather patents from multiple patent holders and offer them to users as a package—is gaining research attention. To bolster the scarce stream of the literature tha...
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Article
Open AccessOral alkalinizing supplementation suppressed intrarenal reactive oxidative stress in mild-stage chronic kidney disease: a randomized cohort study
The beneficial effects of oral supplements with alkalinizing agents in patients with chronic kidney disease (CKD) have been limited to the severe stages. We investigated whether two types of supplements, sodiu...
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Open AccessPolyunsaturated fatty acids-induced ferroptosis suppresses pancreatic cancer growth
Despite recent advances in science and medical technology, pancreatic cancer remains associated with high mortality rates due to aggressive growth and no early clinical sign as well as the unique resistance to...
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Potentials and solutions of cooperative games with a fixed player set
This paper considers the solutions of cooperative games with a fixed player set that admit a potential function. We say that a solution admits a potential function if the solution is given as the marginal cont...
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Open AccessUrinary growth differentiation factor 15 predicts renal function decline in diabetic kidney disease
Sensitive biomarkers can enhance the diagnosis, prognosis, and surveillance of chronic kidney disease (CKD), such as diabetic kidney disease (DKD). Plasma growth differentiation factor 15 (GDF15) levels are a ...
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Open AccessMitochonic acid 5 attenuates age-related neuromuscular dysfunction associated with mitochondrial Ca2+ overload in Caenorhabditis elegans
Mitochonic acid-5 ameliorates the pathophysiology of human mitochondrial-disease fibroblasts and Caenorhabditis elegans Duchenne muscular dystrophy and Parkinson’s disease models. Here, we found that 10 μM MA-5 a...
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Core stability of the Shapley value for cooperative games
Our objective is to analyze the relationship between the Shapley value and the core of cooperative games with transferable utility. We first characterize balanced games, i.e., the set of games with a nonempty ...
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Buck-passing dum** in a garbage-dum** game
We study stable strategy profiles in a pure exchange game of bads, where each player dumps his or her bads such as garbage onto someone else. Hirai et al. (Mathematical Social Sciences 51(2):162–170, 2006) sho...
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Open AccessA non-canonical vitamin K cycle is a potent ferroptosis suppressor
Ferroptosis, a non-apoptotic form of cell death marked by iron-dependent lipid peroxidation1, has a key role in organ injury, degenerative disease and vulnerability of therapy-resistant cancers2. Although substan...
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Open AccessA massive natural disaster, the Great East Japan Earthquake, and the incidence of dialysis due to end-stage kidney disease
Disaster-related stress can increase blood pressure and the incidence of cardiovascular diseases. However, the role of massive disasters in the development of end-stage kidney disease (ESKD) remains unknown. W...
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Mitochonic acid-5 ameliorates chlorhexidine gluconate-induced peritoneal fibrosis in mice
Peritoneal fibrosis is a serious complication of long-term peritoneal dialysis, attributable to inflammation and mitochondrial dysfunction. Mitochonic acid-5 (MA-5), an indole-3-acetic acid derivative, improve...
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Role of the microbiota in hypertension and antihypertensive drug metabolism
Recent evidence suggests that the gut microbiota plays an important role in the development and pathogenesis of hypertension. Dysbiosis, an imbalance in the composition and function of the gut microbiota, was ...
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Open AccessNdufs4 ablation decreases synaptophysin expression in hippocampus
Altered function of mitochondrial respiratory chain in brain cells is related to many neurodegenerative diseases. NADH Dehydrogenase (Ubiquinone) Fe-S protein 4 (Ndufs4) is one of the subunits of mitochondrial...
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Open AccessFibromuscular dysplasia with recurrence after “long-term” following percutaneous transcatheter renal angioplasty: two case reports with a review of 26 patients
Fibromuscular dysplasia (FMD) often causes renal artery stenosis with renovascular hypertension. Recent clinical outcomes encourage percutaneous transluminal renal angioplasty (PTRA) to treat FMD; however, the...
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Identification of characteristic proteins at late-stage erythroid differentiation in vitro
The production of red blood cells in vitro, which is useful for basic or clinical research, has been improved. Further optimization of culture protocols may facilitate erythroid differentiation from hematopoie...
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The projective core of symmetric games with externalities
The purpose of this paper is to study which coalition structures have stable distributions. We employ the projective core as a stability concept. Although the projective core is often defined only for the gran...
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Open AccessL-type amino acid transporter 1 is associated with chemoresistance in breast cancer via the promotion of amino acid metabolism
18F-FDG PET/CT has been used as an indicator of chemotherapy effects, but cancer cells can remain even when no FDG uptake is detected, indicating the importance of exploring other metabolomic pathways. Therefore....
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Concurrent analogous organ damage in the brain, eyes, and kidneys in malignant hypertension: reversible encephalopathy, serous retinal detachment, and proteinuria
Malignant hypertension, a form of hypertensive emergency, causes acute damage in vital organs such as the brain, eyes, and kidneys. We aimed to examine the concurrency of acute hypertensive damage across the t...
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Kidney enlargement effect of angioplasty for nonatherosclerotic renovascular disease: reversibility of ischemic kidney
Renal artery stenosis causes kidney ischemia, reducing the size of the affected kidney, which eventually results in atrophy. Although renal atrophy is considered irreversible, resolution of the ischemia occasi...
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HPRT-related hyperuricemia with a novel p.V35M mutation in HPRT1 presenting familial juvenile gout
Unlike complete deficiency of hypoxanthine phosphoribosyltransferase (HPRT) (i.e., Lesch–Nyhan syndrome), partial HPRT deficiency causes HPRT-related hyperuricemia without neurological symptoms. Herein, we des...
