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Article
Effectiveness and Tolerability of Methotrexate Combined with Biologics in Patients with Crohn’s Disease: A Multicenter Observational Study
Methotrexate (MTX) combination therapy with biological agents has gained increasing interest. Here, we assessed the efficacy and tolerability of the MTX combination therapy in patients with Crohn’s disease (CD).
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Article
Risk factors for post-polypectomy bleeding in patients with end-stage renal disease undergoing colonoscopic polypectomy
Little is known about the risk factors of bleeding after colonoscopic polypectomy in patients with end-stage renal disease (ESRD). This study investigated the incidence and risk factors of post-polypectomy ble...
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Article
Open AccessComparative effectiveness of second-line biological therapies for ulcerative colitis and Crohn’s disease in patients with prior failure of anti-tumour necrosis factor treatment
Therapeutic options for inflammatory bowel disease (IBD) have increased since the introduction of tumour necrosis factor (TNF) inhibitors a few decades ago. However, direct comparisons of the effectiveness of ...
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Article
Open AccessC-reactive protein is associated with postoperative outcomes in patients with intestinal Behçet’s disease
Patients with intestinal Behçet’s disease (BD) frequently undergo intestinal resections, which significantly affects postoperative morbidity and mortality. The aim of this study was to identify the association...
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Article
Outcomes of stent insertion and mortality in obstructive stage IV colorectal cancer patients through 10 year duration
Colorectal stents are frequently used in patients with stage IV colorectal cancer with obstruction. However, there are only few studies on changes in outcomes of these patients and on the effect of stents on o...
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Article
Does Medical Acceleration Improve Outcomes in Ulcerative Colitis Patients Who Are in Clinical Remission but Have Endoscopic Inflammation?
Discrepancies between clinical symptoms and mucosal inflammation have been reported in up to 50% of patients with ulcerative colitis (UC). However, there are no guidelines and only limited information for appr...
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Article
Extensive Disease Subtypes in Adult Patients with Ulcerative Colitis: Non-pancolitis Versus Pancolitis
Few studies have compared pancolitis and non-pancolitis E3 in adult patients with ulcerative colitis (UC). This study aimed to evaluate the natural disease courses and factors affecting outcomes between pancol...
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Article
Risk factors and clinical courses of concomitant primary sclerosing cholangitis and ulcerative colitis: a Korean multicenter study
Primary sclerosing cholangitis (PSC) is a rare progressive cholestatic liver disease of unknown causes, but is strongly associated with inflammatory bowel diseases (IBDs), particularly ulcerative colitis (UC)....
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Article
Long-term outcomes after stenting as a bridge to surgery in patients with obstructing left-sided colorectal cancer
Self-expandable metallic stents (SEMS) may be used in acute, obstructing, left-sided colorectal cancer (CRC) to avoid high-risk emergency surgery. However, the data regarding the long-term effects of SEMS as a...
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Article
The effect of metformin on the recurrence of colorectal adenoma in diabetic patients with previous colorectal adenoma
Existing studies suggest that metformin lowers the risk and mortality of colorectal cancer. However, the effect of metformin on the suppression and prevention of colorectal adenomas is not clear. The aim of th...
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Article
Proteomic Analysis of Serum Amyloid A as a Potential Marker in Intestinal Behçet’s Disease
Data regarding biomarkers to understand disease pathogenesis and to assess disease activity of intestinal Behçet’s disease (BD) are limited. Therefore, we aimed to investigate the differentially expressed prot...
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Article
Risk factors and outcomes of acute lower gastrointestinal bleeding in intestinal Behçet’s disease
Intestinal Behçet’s disease (BD) can cause acute lower gastrointestinal bleeding, which is sometimes fatal.
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Article
The outcomes and risk factors of early reoperation after initial intestinal resective surgery in patients with intestinal Behçet’s disease
Patients with intestinal Behçet’s disease who underwent intestinal resective surgery often require reoperation. However, there have been no studies on the risk factors and outcomes of early reoperation in thes...
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Article
Probe-based confocal laser endomicroscopy for evaluating the submucosal invasion of colorectal neoplasms
Probe-based confocal laser endomicroscopy (pCLE) is a novel method for in vivo histological analysis of colorectal neoplasm mucosa, which provides meaningful information for the development of adequate therape...
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Article
Tumor characteristics associated with malignant large bowel obstruction in stage IV colorectal cancer patients undergoing chemotherapy
Little is known about predictable clinical factors associated with the occurrence of malignant large bowel obstruction (MLBO) in incurable stage IV colorectal cancer (CRC) patients undergoing medical treatment...
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Article
Postoperative Effects of Thiopurines in Patients with Intestinal Behçet’s Disease
No studies have heretofore specifically focused on the efficacy of postoperative thiopurine therapy in intestinal Behçet’s disease (BD). We conducted this study to assess the clinical effects of postoperative ...
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Article
Seasonal Variation in Flares of Intestinal Behçet’s Disease
There have been numerous investigations into the seasonality of several autoimmune diseases and inflammatory bowel disease in an effort to better understand the epidemiology and pathogenesis of these condition...
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Article
What is the necessity of endoscopist for successful endoscopic stenting in patients with malignant colorectal obstruction?
Recently, self-expandable metal stents (SEMSs) have been widely used as an initial therapy for relieving malignant colorectal obstructions. However, several factors, including the endoscopist’s experience, aff...
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Article
Leukopenia Predicts Remission in Patients with Inflammatory Bowel Disease and Behcet’s Disease on Thiopurine Maintenance
The thiopurine drugs, azathioprine (AZA), and 6-mercaptopurine (6-MP) are well-established drugs for the treatment of inflammatory bowel disease (IBD). Although leukopenia is a well-recognized side effect of A...
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Article
Mucosal Healing Predicts the Long-Term Prognosis of Intestinal Behçet’s Disease
Mucosal healing (MH) has emerged as a therapeutic goal in the treatment of inflammatory bowel disease; however, little is known about the impact of MH on the prognosis of intestinal Behçet’s disease (BD).