7 Result(s)
within
Tae-Soo Kim
Oncology
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Article
Open AccessScreening mammography performance according to breast density: a comparison between radiologists versus standalone intelligence detection
Artificial intelligence (AI) algorithms for the independent assessment of screening mammograms have not been well established in a large screening cohort of Asian women. We compared the performance of screenin...
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Article
Inhibition of the bromodomain and extra-terminal family of epigenetic regulators as a promising therapeutic approach for gastric cancer
Epigenetic dysregulation is a common characteristic of cancers, including gastric cancer (GC), and contributes to cancer development and progression. Although the efficacy of BET (an epigenetic regulator) inhi...
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Article
Inhibiting casein kinase 2 overcomes paclitaxel resistance in gastric cancer
Casein kinase (CK) 2 activation has been implicated in the proliferation of various tumor types and resistance to chemotherapy. We investigated the mechanistic basis for the association between CK2 activation ...
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Article
Open AccessComprehensive immune profiling and immune-monitoring using body fluid of patients with metastatic gastric cancer
The aim of this study is to profile the cytokines and immune cells of body fluid from metastatic gastric cancer (mGC), and evaluate the potential role as a prognostic factor and the feasibility as a predictive...
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Article
Identification of genes associated with chemosensitivity to SAHA/taxane combination treatment in taxane-resistant breast cancer cells
Here we evaluated the cytotoxic effects of a combination of the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) and taxanes in human breast cancer cell lines. Combination treatment with ta...
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Article
Identification of genes related to a synergistic effect of taxane and suberoylanilide hydroxamic acid combination treatment in gastric cancer cells
We evaluated the cytotoxic effects of combining suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, with taxanes in human gastric cancer cell lines and assessed the pre-treatment differenc...
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Chapter
Selenium-induced apoptosis
Selenium is both an essential and a toxic trace element. It has been reported to induce cell growth and cell proliferation, but also cell death by necrosis or apoptosis. The biological action of selenium is de...
