-
Article
Open AccessECMO is associated with decreased hospital mortality in COVID-19 ARDS
This study determined whether compared to conventional mechanical ventilation (MV), extracorporeal membrane oxygenation (ECMO) is associated with decreased hospital mortality or fibrotic changes in patients wi...
-
Article
Open AccessTime division multiplexing based multi-spectral semantic camera for LiDAR applications
The recent progress in the development of measurement systems for autonomous recognition had a substantial impact on emerging technology in numerous fields, especially robotics and automotive applications. In ...
-
Article
Open AccessGlobal intracranial arterial tortuosity is associated with intracranial atherosclerotic burden
The effect of arterial tortuosity on intracranial atherosclerosis (ICAS) is not well understood. This study aimed to evaluate the effect of global intracranial arterial tortuosity on intracranial atherosclerot...
-
Article
Open AccessCorrection: Inflammation promotes synucleinopathy propagation
-
Article
Open AccessLoss of SREBP-1c ameliorates iron-induced liver fibrosis by decreasing lipocalin-2
Sterol regulatory element-binding protein (SREBP)-1c is involved in cellular lipid homeostasis and cholesterol biosynthesis and is highly increased in nonalcoholic steatohepatitis (NASH). However, the molecula...
-
Article
Open AccessApplication of natural orifice transluminal endoscopic surgery with ENDOCRAB system for stomach perforation model: ex vivo porcine study
Iatrogenic stomach perforation is a detrimental, irreversible, and fatal condition. Traditional surgery and endoscopic suturing clips and devices have been introduced to seal holes and prevent sepsis and disea...
-
Article
Open AccessFully bioresorbable hybrid opto-electronic neural implant system for simultaneous electrophysiological recording and optogenetic stimulation
Bioresorbable neural implants based on emerging classes of biodegradable materials offer a promising solution to the challenges of secondary surgeries for removal of implanted devices required for existing neu...
-
Article
Open AccessExploring the Smoking-Epilepsy Nexus: a systematic review and meta-analysis of observational studies
Epilepsy, characterized by recurrent unprovoked seizures, poses significant challenges to affected individuals globally. While several established risk factors for epilepsy exist, the association with cigarett...
-
Article
Open AccessDeep Learning-Based Detection of Defects in Wafer Buffer Zone During Semiconductor Packaging Process
Effectively detecting defects in wafer buffer zones is crucial in semiconductor manufacturing processes. If defects are not detected in the middle of the semiconductor manufacturing process, the semiconductor ...
-
Article
Open AccessMetabolic engineering of Caldicellulosiruptor bescii for hydrogen production
Hydrogen is an alternative fuel for transportation vehicles because it is clean, sustainable, and highly flammable. However, the production of hydrogen from lignocellulosic biomass by microorganisms presents c...
-
Article
Open AccessSemi-empirical approach to assess externally-induced photoluminescence linewidth broadening of halide perovskite nanocrystals with particle-size distribution
Colloidal nanocrystals (NCs) can be used to prepare high-color-purity metal halide perovskites (MHPs) for light-emitting displays. However, the NCs have a finite particle-size distribution, which broadens the ...
-
Article
Correction: Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 ameliorates symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pathology
-
Article
Correction to: Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 ameliorates symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pathology
-
Article
Open AccessCancer signature ensemble integrating cfDNA methylation, copy number, and fragmentation facilitates multi-cancer early detection
Cell-free DNA (cfDNA) sequencing has demonstrated great potential for early cancer detection. However, most large-scale studies have focused only on either targeted methylation sites or whole-genome sequencing...
-
Article
Open AccessAngiotensin receptor blockers, but not angiotensin-converting enzyme inhibitors, inhibit abnormal bone changes in spondyloarthritis
Spondyloarthritis (SpA) is a chronic inflammatory disease that results in bone ankylosis. The tissue renin-angiotensin system (RAS) is an emerging pathway potentially implicated in SpA-associated bone changes....
-
Article
Open AccessMicro-syringe chip-guided intratumoral administration of lipid nanoparticles for targeted anticancer therapy
Nano-sized drug delivery system has been widely studied as a potential technique to promote tumor-specific delivery of anticancer drugs due to its passive targeting property, but resulting in very restricted i...
-
Article
Open AccessSafety and Effectiveness of Regdanvimab for COVID-19 Treatment: A Phase 4 Post-marketing Surveillance Study Conducted in South Korea
Regdanvimab, a neutralising monoclonal antibody (mAb) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), received approval for the treatment of coronavirus disease 2019 (COVID-19) in South K...
-
Article
Open AccessAssociation between SLCO1B1 genetic polymorphisms and bleeding risk in patients treated with edoxaban
Since SLCO1B1 encodes the uptake transporter OATP1B1, which can influence the pharmacokinetic and pharmacodynamic profiles of edoxaban, polymorphisms in SLCO1B1 may affect the edoxaban response. This study aimed ...
-
Article
Open AccessStrong Rashba parameter of two-dimensional electron gas at CaZrO3/SrTiO3 heterointerface
We synthesized a CaZrO3/SrTiO3 oxide heterostructure, which can serve as an alternative to LaAlO3/SrTiO3, and confirmed the generation of 2-dimensional electron gas (2-DEG) at the heterointerface. We analyzed the...
-
Article
Open AccessThe lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism
Arachidonic and adrenic acids in the membrane play key roles in ferroptosis. Here, we reveal that lipoprotein-associated phospholipase A2 (Lp-PLA2) controls intracellular phospholipid metabolism and contribute...
