76 Result(s)

Article

Sustained remission after cord blood transplantation for breast cancer with lung metastases and myelodysplastic syndrome

Allogenic hematopoietic stem cell transplantation (allo-HSCT) is not a standard therapy for solid cancer because of its high toxicity and insufficient evidence levels. However, the potential graft-versus-solid...

Naokazu Nakamura, Nao Yamamoto, Tadakazu Kondo… in International Journal of Hematology (2024)

Article

Allogeneic hematopoietic cell transplantation for patients with acute myeloid leukemia not in remission

Allogeneic hematopoietic cell transplantation (HCT) is the last option for long-term survival for patients with chemotherapy-refractory acute myeloid leukemia (AML). By using the Japanese nationwide registry d...

Masamitsu Yanada, Satoshi Yamasaki, Tadakazu Kondo, Takahito Kawata… in Leukemia (2024)

Article

Pretreatment blast-to-lymphocyte ratio as a prognostic marker for CD19/CD3-bispecific T cell-engaging antibodies (blinatumomab) treatment against relapsed or refractory B-precursor acute lymphoblastic leukemia

Blinatumomab is an immunotherapy drug approved for the treatment of acute lymphoblastic leukemia. Since not all patients respond to blinatumomab, markers are needed to predict the efficacy of blinatumomab in i...

Yutaka Shimazu, Toshio Kitawaki, Tadakazu Kondo… in Cancer Immunology, Immunotherapy (2023)

Article

External validation and extended application of the transplant conditioning intensity score in acute myeloid leukemia

This study aimed to validate the utility of the transplant conditioning intensity (TCI) score in 1714 patients with acute myeloid leukemia (AML) undergoing allogeneic bone marrow or peripheral blood stem cell ...

Masamitsu Yanada, Yoshimitsu Shimomura, Shohei Mizuno… in Bone Marrow Transplantation (2023)

Article

Effects of combined test dose and therapeutic drug monitoring strategy in exposure-directed busulfan

Although exposure-directed busulfan (BU) dosing can improve allogeneic hematopoietic stem cell transplantation outcomes, there is still large variability in BU exposure with test dose alone due to changes in ...

Tomoki Iemura, Tadakazu Kondo, Atsushi Ueda, Takeshi Maeda… in Annals of Hematology (2023)

Article

Clinical characteristics of late-onset interstitial pneumonia after allogeneic hematopoietic stem cell transplantation

Non-infectious pulmonary complications after allogeneic hematopoietic stem cell transplantation (HSCT) remain fatal. In particular, information regarding late-onset interstitial lung disease predominantly incl...

Nobuharu Fujii, Makoto Onizuka, Takahiro Fukuda… in International Journal of Hematology (2023)

Article

Salvage single-unit unrelated cord blood transplantation for graft failure following initial allogeneic transplantation in adult acute myeloid leukemia: trends in outcomes over the past 20 years

Takaaki Konuma, Kaito Harada, Tadakazu Kondo… in Bone Marrow Transplantation (2022)

Article

Improved survival after single-unit cord blood transplantation using fludarabine and melphalan-based reduced-intensity conditioning for malignant lymphoma: impact of melphalan dose and graft-versus-host disease prophylaxis with mycophenolate mofetil

We evaluated 413 adult patients with lymphoma who underwent unrelated cord blood transplantation (UCBT) with fludarabine and melphalan (FM)-based reduced-intensity conditioning between 2002 and 2017 to investi...

Kazuki Sakatoku, Sung-Won Kim, Hiroshi Okamura, Minoru Kanaya… in Annals of Hematology (2022)

Article

Resignation and return to work in patients receiving allogeneic hematopoietic cell transplantation close up

To characterize the issues regarding work and employment specific to allogeneic hematopoietic cell transplantation (allo-HCT) survivors, we conducted a nationwide cross-sectional questionnaire survey.

Saiko Kurosawa, Takuhiro Yamaguchi, Ayako Mori… in Journal of Cancer Survivorship (2022)

Article

Feasibility of ovarian stimulation for fertility preservation during and after blinatumomab treatment for Ph-negative B-cell acute lymphoblastic leukemia

It is challenging to preserve the fertility of female patients with B-cell acute lymphoblastic leukemia (B-ALL) before allogeneic hematopoietic stem cell transplantation (allo-HSCT) while maintaining treatment...

Yusuke Tashiro, Junya Kanda, Tomoki Iemura… in International Journal of Hematology (2022)

Article

Addition and drug monitoring of mycophenolate mofetil for GVHD prophylaxis in unrelated bone marrow transplantation

Fumiya Wada, Tadakazu Kondo, Ryusuke Yamamoto… in Bone Marrow Transplantation (2022)

Article

Improved outcomes of single-unit cord blood transplantation for acute myeloid leukemia by killer immunoglobulin-like receptor 2DL1-ligand mismatch

The impact of the killer immunoglobulin-like receptor (KIR)-ligand mismatch between donor and recipient in hematopoietic stem cell transplantation is controversial. Recently, it has been suggested that their e...

Hisayuki Yokoyama, Minoru Kanaya, Tomoki Iemura… in Bone Marrow Transplantation (2022)

Article

Successful allogeneic bone marrow transplantation in a case of variant acute promyelocytic leukemia with ZBTB16-RARA

Suguru Morimoto, Tadakazu Kondo, Tomohiro Taya, Hidemasa Matsuo… in Annals of Hematology (2022)

Article

Evaluation of indices for predicting recovery of exercise tolerance in patients surviving allogenic hematopoietic stem cell transplantation

Decline in physical function in the early stage after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a major challenge. Exercise tolerance tests, such as the 6-min walk test, are useful mark...

Ryota Hamada, Tadakazu Kondo, Kazuhiro Harada, Masanobu Murao… in Supportive Care in Cancer (2022)

Article

Coexistence of HLA and KIR ligand mismatches as a risk factor for viral infection early after cord blood transplantation

Viral infection is one of the lethal adverse events after cord blood transplantation (CBT). Human leukocyte antigen (HLA) and killer immunoglobulin-like receptor (KIR) ligand divergences can increase the risk ...

Tomoki Iemura, Yasuyuki Arai, Toshio Kitawaki, Junya Kanda… in Bone Marrow Transplantation (2022)

Article

Comparing cord blood transplantation and matched related donor transplantation in non-remission acute myeloid leukemia

Cord blood transplantation (CBT) is an alternative donor transplantation method and has the advantages of rapid availability and the possibility of inducing a more potent graft-versus-leukemia effect, leading ...

Yoshimitsu Shimomura, Tomotaka Sobue, Shigeki Hirabayashi, Tadakazu Kondo… in Leukemia (2022)