22 Result(s)

Article

Allogeneic hematopoietic cell transplantation for patients with acute myeloid leukemia not in remission

Allogeneic hematopoietic cell transplantation (HCT) is the last option for long-term survival for patients with chemotherapy-refractory acute myeloid leukemia (AML). By using the Japanese nationwide registry d...

Masamitsu Yanada, Satoshi Yamasaki, Tadakazu Kondo, Takahito Kawata… in Leukemia (2024)

Article

External validation and extended application of the transplant conditioning intensity score in acute myeloid leukemia

This study aimed to validate the utility of the transplant conditioning intensity (TCI) score in 1714 patients with acute myeloid leukemia (AML) undergoing allogeneic bone marrow or peripheral blood stem cell ...

Masamitsu Yanada, Yoshimitsu Shimomura, Shohei Mizuno… in Bone Marrow Transplantation (2023)

Article

Salvage single-unit unrelated cord blood transplantation for graft failure following initial allogeneic transplantation in adult acute myeloid leukemia: trends in outcomes over the past 20 years

Takaaki Konuma, Kaito Harada, Tadakazu Kondo… in Bone Marrow Transplantation (2022)

Article

Addition and drug monitoring of mycophenolate mofetil for GVHD prophylaxis in unrelated bone marrow transplantation

Fumiya Wada, Tadakazu Kondo, Ryusuke Yamamoto… in Bone Marrow Transplantation (2022)

Article

Improved outcomes of single-unit cord blood transplantation for acute myeloid leukemia by killer immunoglobulin-like receptor 2DL1-ligand mismatch

The impact of the killer immunoglobulin-like receptor (KIR)-ligand mismatch between donor and recipient in hematopoietic stem cell transplantation is controversial. Recently, it has been suggested that their e...

Hisayuki Yokoyama, Minoru Kanaya, Tomoki Iemura… in Bone Marrow Transplantation (2022)

Article

Coexistence of HLA and KIR ligand mismatches as a risk factor for viral infection early after cord blood transplantation

Viral infection is one of the lethal adverse events after cord blood transplantation (CBT). Human leukocyte antigen (HLA) and killer immunoglobulin-like receptor (KIR) ligand divergences can increase the risk ...

Tomoki Iemura, Yasuyuki Arai, Toshio Kitawaki, Junya Kanda… in Bone Marrow Transplantation (2022)

Article

Comparing cord blood transplantation and matched related donor transplantation in non-remission acute myeloid leukemia

Cord blood transplantation (CBT) is an alternative donor transplantation method and has the advantages of rapid availability and the possibility of inducing a more potent graft-versus-leukemia effect, leading ...

Yoshimitsu Shimomura, Tomotaka Sobue, Shigeki Hirabayashi, Tadakazu Kondo… in Leukemia (2022)

Article

Human leukocyte antigen (HLA) haplotype matching in unrelated single HLA allele mismatch bone marrow transplantation

The role of matching human leukocyte antigen (HLA) haplotypes in unrelated allogeneic bone marrow transplantation (allo-BMT) remains unclear. Here, we imputed the HLA haplotypes of 3657 patients who received u...

Akihisa Kawajiri, Takakazu Kawase, Hidenori Tanaka… in Bone Marrow Transplantation (2022)

Article

Impact of donor types on reduced-intensity conditioning allogeneic stem cell transplant for mature lymphoid malignancies

We retrospectively compared the outcomes of reduced-intensity conditioning (RIC) transplantation from matched related donors (MRD; n = 266), matched unrelated donors (MUD; n = 277), and umbilical cord blood (UCB;...

Nobuhiko Imahashi, Seitaro Terakura, Eisei Kondo, Koji Kato… in Bone Marrow Transplantation (2022)

Article

Impact of HLA disparity on the risk of overall mortality in patients with grade II–IV acute GVHD on behalf of the HLA Working Group of Japan Society for Hematopoietic Cell Transplantation

Acute graft-versus-host disease (aGVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation (HCT). Stem cell source or HLA disparity may exert a significant impact o...

Shigeo Fuji, Akitoshi Hakoda, Junya Kanda, Makoto Murata… in Bone Marrow Transplantation (2021)

Article

Impact of conditioning intensity and regimen on transplant outcomes in patients with adult T-cell leukemia-lymphoma

In allogeneic hematopoietic cell transplantation (allo-HCT) for adult T-cell leukemia-lymphoma (ATL), the optimal conditioning regimens have not yet been determined. We conducted a Japanese nationwide, retrosp...

Yoshitaka Inoue, Nobuaki Nakano, Shigeo Fuji, Tetsuya Eto… in Bone Marrow Transplantation (2021)

Article

Prognostic value of measurable residual disease at allogeneic transplantation for adults with core binding factor acute myeloid leukemia in complete remission

Pretransplant measurable residual disease (MRD) has been shown to be associated with relapse incidence following allogeneic hematopoietic cell transplantation (HCT) for acute myeloid leukemia (AML). However, i...

Takaaki Konuma, Tadakazu Kondo, Masayoshi Masuko… in Bone Marrow Transplantation (2021)

Article

Impact of the combination of donor age and HLA disparity on the outcomes of unrelated bone marrow transplantation

Impact of donor age considering HLA disparity on hematopoietic cell transplantation (HCT) outcomes has not been fully evaluated. We evaluated 8486 patients who received unrelated bone marrow transplantation (U...

Sachiko Seo, Yoshiaki Usui, Keitaro Matsuo, Yoshiko Atsuta… in Bone Marrow Transplantation (2021)

Article

Comparison of fludarabine, a myeloablative dose of busulfan, and melphalan vs conventional myeloablative conditioning regimen in patients with relapse and refractory acute myeloid leukemia in non-remission status

Yoshimitsu Shimomura, Masahiko Hara, Shigeki Hirabayashi… in Bone Marrow Transplantation (2021)

Article

Relapse of acute myeloid leukemia after allogeneic hematopoietic cell transplantation: clinical features and outcomes

Posttransplant relapse represents the greatest obstacle to the success of allogeneic hematopoietic cell transplantation (HCT) for patients with acute myeloid leukemia (AML). This study investigated clinical fe...

Masamitsu Yanada, Takaaki Konuma, Satoshi Yamasaki… in Bone Marrow Transplantation (2021)

Article

Predicting non-relapse mortality following allogeneic hematopoietic cell transplantation during first remission of acute myeloid leukemia

The aim of this study was to develop a comprehensive system for predicting non-relapse mortality after allogeneic hematopoietic cell transplantation (HCT) during first complete remission (CR) of acute myeloid ...

Masamitsu Yanada, Takaaki Konuma, Shohei Mizuno… in Bone Marrow Transplantation (2021)

Article

Reduced-intensity stem cell transplantation for acute myeloid leukemia with fludarabine-based conditioning with intravenous busulfan versus melphalan

Reduced-intensity conditioning (RIC) has been facilitating allogeneic hematopoietic cell transplantation (allo-HCT) for patients originally considered ineligible for HCT with myeloablative conditioning. Fludar...

Takuya Yamashita, Akiyoshi Takami, Naoyuki Uchida… in Bone Marrow Transplantation (2020)

Article

Unit selection for umbilical cord blood transplantation for adults with acute myeloid leukemia in complete remission: a Japanese experience

To investigate optimal unit selection for umbilical cord blood transplantation (UCBT), we conducted a registry-based study of 1355 adults with acute myeloid leukemia in first or second complete remission who u...

Masamitsu Yanada, Takaaki Konuma, Yachiyo Kuwatsuka… in Bone Marrow Transplantation (2019)

Article

Effectiveness of cord blood transplantation for the treatment of refractory angioimmunoblastic T-cell lymphoma: a series of three cases

Yasuhiro Kazuma, Yayoi Shimazu, Masakatsu Hishizawa… in Bone Marrow Transplantation (2019)

Article

Employment status was highly associated with quality of life after allogeneic hematopoietic cell transplantation, and the association may differ according to patient age and graft-versus-host disease status: analysis of a nationwide QOL survey

Saiko Kurosawa, Takuhiro Yamaguchi, Kumi Oshima… in Bone Marrow Transplantation (2019)