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Article
An adult form of Alexander disease: a novel mutation in glial fibrillary acidic protein
Glial fibrillary acidic protein (GFAP) mutation has been reported in Alexander disease. We report a patient with the adult form of Alexander disease who shows a novel mutation in GFAP. This case presented with pr...
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Article
Endovascular treatment of basilar tip aneurysms associated with moyamoya disease
We report the efficacy and safety of endovascular treatment of basilar tip aneurysms (BTA) in five patients with moyamoya disease. The patients underwent intra-aneurysmal embolisation with detachable platinum ...
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Article
Delayed Cerebral Radiation Necrosis Occurring Twice at Different Regions and Times in a Patient with a Metastatic Brain Tumour
¶ No case of histopathologically confirmed delayed cerebral radiation necrosis (DCRN) that occurred twice at different regions and times in the same patient has been previously reported. We present a patient w...
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Article
Demonstration of the Optic Pathway in Sellar/Juxtasellar Tumours with Visual Disturbance on MR Imaging
Objective. To prospectively compare the demonstration of the intracranial optic pathway in patients with sellar/juxtasellar tumours and with clinical evidence of visual disturbance using either spoiled gradient ...
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Article
MIB1 immunopositivity is associated with rapid regrowth of pituitary adenomas
Pituitary adenomas are generally regarded as benign tumours, but they may recur. We identified eight patients with pituitary adenomas that showed rapid regrowth within 2 years of initial surgery. We estimated ...
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Article
Matrix metalloproteinase-9 secretion by human pituitary adenomas detected by cell immunoblot analysis
Twenty-two pituitary adenomas were examined on the secretion of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) using a cell immunoblot assay, and discussed regarding an...
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Article
Type IV collagenase activity and cavernous sinus invasion in human pituitary adenomas
Pituitary adenomas are regarded generally as benign tumours, but some of them can invade the cavernous sinus. On the other hand, matrix metalloproteinase-9 (MMP-9), which is a type IV collagenase, recently has...
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Article
MRI of pineal region tumours: relationship between tumours and adjacent structures
A variety of tumours may arise in the pineal region; accurate diagnosis is important in the selection of treatment and prognosis. A retrospective analysis of the MRI studies of 25 patients with pathologically ...
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Article
Spontaneous disappearance of an aneurysmal malformation of the vein of Galen
We describe spontaneous disappearance of an aneurysmal malformation of the vein of Galen (AMG), an anomaly that occurs most often in children, with a high mortality due to the accompanying severe cardiac failu...
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Article
Analysis of the growth rate and cavernous sinus invasion of pituitary adenomas
Pituitary adenomas generally are regarded as benign tumours, but a part of them can invade the cavernous sinus and recur. We examined 43 pituitary adenomas for the following factors: tumour volume, endocrinolo...
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Article
Surface anatomy scanning (SAS) in intracranial tumours: comparison with surgical findings
We evaluated the usefulness of surface anatomy scanning (SAS) in intracranial tumours, comparing it with surgical findings. We examined 31 patients with brain tumours preoperatively. The tumours included 16 me...
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Chapter and Conference Paper
Use of fast spin-echo sequence in T2-weighted and dynamic contrast-enhanced MRI of sellar lesions
We evaluated fast spin echo (FSE) sequences in dynamic and T2-weighted MRI of sellar lesions. We examined 25 patients with sellar lesions by dynamic FSE imaging (400/17, ETL 8, 256 × 128, 2 signal averages eve...
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Chapter and Conference Paper
MR angiography of arteriovenous malformations: usefulness of phase-contrast with different velocity encoding
To evaluate the usefulness of MR angiography in arteriovenous malformations (AVM) and compare the phase-contrast (PC) with different velocity encoding (VENC) and time-of-flight (TOF) techniques, we prospective...
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Article
MRI of intracranial germ cell tumors
We reviewed MRI findings in proven intracranial germ cell tumours in 22 cases, 12 of whom received Gd-DTPA. On T1-weighted images, the signal intensity of the tumour parenchyma was moderately low in 19 cases a...
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Chapter and Conference Paper
Utility of MR angiography in intracranial aneurysms: statistical correlation and surgical benefits of the 3-D time-of-flight method
We evaluated the clinical benefit of three-dimensional (3-D) time-of-flight (TOF) MR angiography (MRA) and spoiled GRASS (SPGR) source imaging for intracranial aneurysms. MRA was performed on 40 aneurysms conf...
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Article
Embolisation of orbital varix
A 34-year-old man with intermittent exophthalmos, found to have a large varix in the right orbit, was treated by endovascular surgery. Percutaneous transfemoral venous catheterisation and embolisation of the o...
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Article
Displacement of the normal pituitary gland by sellar and juxtasellar tumours: surgical-MRI correlation and use in differential diagnosis
We compared the position of the normal pituitary gland as estimated by gadolinium (Gd)-DTPA-enhanced MRI, with its position at surgery in 40 patients with intra- and juxtasellar tumours: 22 pituitary adenomas,...
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Article
MRI of pituitary adenomas: the position of the normal pituitary gland
The position of the normal pituitary gland, assessed using gadolinium-enhanced MRI was compared with the position found at surgery for pituitary adenoma in 25 patients. The tumours were five microadenomas and ...
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Article
MRI visualization of complete bilateral optic nerve involvement by pituitary adenoma: a case report
With large pituitary adenomas, the optic nerves and chiasm usually lie on the tumour capsule and are displaced superiorly. We report a large invasive pituitary adenoma, with complete involvement of both optic ...
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Article
Hyperaemia prior to acute cerebral swelling in severe head injuries: The role of transcranial doppler monitoring
Acute cerebrovascular congestion after a closed head injury is significantly related to intracranial hypertension. As an indirect method of cerebral blood flow measurement, transcranial doppler sonography (TCD...