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Protocol
Three-Vessel Middle Cerebral Artery Occlusion Model
In the search for a more reproducible focal ischemic stroke model in the rat, we systematically interrupted blood flow to the right middle cerebral artery (MCA) territory by transient ligation of the right MCA...
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Reference Work Entry In depth
Cerebral Endothelial Cell Reaction to Ischemic Insults
Clinical as well as basic research in the past decades has revealed the crucial importance of cerebral endothelial cell (CEC) dysfunction contributing to secondary injury following primary brain ischemic insul...
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Chapter and Conference Paper
Neurotrophin Expression and Gene Regulation in a Focal Cerebral Ischemia Model in the Rat
Injury to the central nervous system (CNS) is accompanied by increased release of neurotransmitter into extracellular space. Neurotransmitter actions may invoke two sequential responses. The first is an immedi...