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within T. M. Ayodele Adesanya Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

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  1. Article

    Open Access

    MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

    TRIM family proteins play integral roles in the innate immune response to virus infection. MG53 (TRIM72) is essential for cell membrane repair and is believed to be a muscle-specific TRIM protein. Here we show...

    Matthew Sermersheim, Adam D. Kenney, Pei-Hui Lin… in Nature Communications (2020)

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  2. Article

    Open Access

    Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function

    MG53 is a muscle-specific TRIM-family protein that presides over the cell membrane repair response. Here, we show that MG53 present in blood circulation acts as a myokine to facilitate tissue injury-repair and...

    Zehua Bian, Qiang Wang, **nyu Zhou, Tao Tan, Ki Ho Park… in Nature Communications (2019)

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