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  1. Article

    Open Access

    Adiponectin deficiency exacerbates age-related hearing impairment

    Obesity-related disorders are closely associated with the development of age-related hearing impairment (ARHI). Adiponectin (APN) exerts protective effects against obesity-related conditions including endothel...

    T Tanigawa, R Shibata, N Ouchi, K Kondo, M Ishii, N Katahira… in Cell Death & Disease (2014)

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    Article

    A thiol protease of peritoneal macrophages in the guinea pig

    Proteolytic enzymes of the guinea pig peritoneal exudate macrophages were investigated using synthetic fluorogenic peptide substrates. Among several enzymes, t-butyloxycarbonyl-phenylalanyl-seryl-arginine 4-me...

    T. Kambara, S. Uchida, J. Tanaka, S. Shoji in Experientia (1986)

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    Article

    An alkaline protease in the delayed hypersensitivity skin lesions in the guinea-pigs

    An alkaline hemoglobinolytic protease was extracted from the delayed hypersensitivity skin lesions induced by bovine γ-globulin as an antigen in the guinea-pig. The enzyme was heat-labile and inhibited by thio...

    T. Kambara, M. Hashimoto in Experientia (1979)

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    Article

    Neutral proteases in the guinea-pig lymphocytes

    Partial purification of neutral proteolytic enzymes in guinea-pig lymphocytes yielded 2 enzymes. Both enzymes were heat-labile and inhibited by thiol reagents. The molecular weights were more than 200,000 and ...

    T. Kambara, M. Hirata, T. Hiraoka in Experientia (1978)