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  1. No Access

    Article

    Promoter Hypermethylation Frequency and BRAF Mutations Distinguish Hereditary Non-Polyposis Colon Cancer from Sporadic MSI-H Colon Cancer

    Background: Colorectal cancers resulting from defective DNA mismatch repair can occur in both hereditary non-polyposis colon cancer (HNPCC) and in the sporadic setting. They are characterised by a high level of ...

    A. McGivern, C.V.A. Wynter, V.L.J. Whitehall, T. Kambara, K.J. Spring… in Familial Cancer (2004)

  2. No Access

    Article

    Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice

    Murine L5178Y-ML cells, when transplanted subcutaneously into the flank of (BALB/c x DBA/2)F1 mice, grew locally and always formed spontaneous metastases in the liver. Even after surgical removal of the primar...

    S Sugihara, T Yamamoto, H Tanaka, T Kambara, T Hiraoka… in British Journal of Cancer (1993)

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    Article

    Substance P as a potent stimulator of sneeze responses in experimental allergic rhinitis of guinea pigs

    Substance P was examined for sneeze-inducing activity and its involvement of sneeze responses in experimental allergic rhinitis. Substance P, dripped into a nostril of guinea pigs, at concentrations of 100 pM and...

    Dr. T. Imamura, T. Kambara in Agents and Actions (1992)

  4. No Access

    Article

    Serine protease-induced enhancement of blood-borne metastasis of rat ascites tumour cells and its prevention with deoxyribonuclease

    Serine proteases, such as alpha-chymotrypsin or elastase, caused an aggregation of rat ascites tumour cell lines, AH-130, AH-109A and YS, in a protein free medium which preserved the cell viability. This aggre...

    S Sugihara, T Yamamoto, J Tsuruta, J Tanaka, T Kambara… in British Journal of Cancer (1990)