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    Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

    Heterozygous carriers of germ-line mutations in the BRCA2/FANCD1, PALB2/FANCN and RAD51C/FANCO DNA repair genes have an increased lifetime risk of develo** breast, ovarian and other cancers; bi-allelic mutation...

    J-Y Park, T R Singh, N Nassar, F Zhang, M Freund, H Hanenberg, A R Meetei… in Oncogene (2014)