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    Article

    Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

    Solveig Gretarsdottir, Kari Stefansson and colleagues report a genome-wide association study for abdominal aortic aneurysm. They identified a variant located within the DAB2IP gene on 9q33 associated with risk of...

    Solveig Gretarsdottir, Annette F Baas, Gudmar Thorleifsson, Hilma Holm in Nature Genetics (2010)

  2. Article

    Open Access

    SUrgical versus PERcutaneous Bypass: SUPERB-trial; Heparin-bonded endoluminal versus surgical femoro-popliteal bypass: study protocol for a randomized controlled trial

    Endovascular treatment options for the superficial femoral artery are evolving rapidly. For long lesions, the venous femoropopliteal bypass considered to be superior above the prosthetic bypass. An endoluminal...

    Mare MA Lensvelt, Suzanne Holewijn, Wilbert M Fritschy, Otmar RM Wikkeling in Trials (2011)

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    Article

    Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders

    Ruth Loos and colleagues report a meta-analysis of genome-wide association studies in 181,171 individuals identifying 14 new loci associated with heart rate and test these for association with cardiac conducti...

    Marcel den Hoed, Mark Eijgelsheim, Tõnu Esko, Bianca J J M Brundel in Nature Genetics (2013)

  4. Article

    Open Access

    Mechanochemical endovenous Ablation versus RADiOfrequeNcy Ablation in the treatment of primary great saphenous vein incompetence (MARADONA): study protocol for a randomized controlled trial

    Radiofrequency ablation (RFA) is associated with an excellent outcome in the treatment of great saphenous vein (GSV) incompetence. The use of thermal energy as a treatment source requires the instillation of t...

    Ramon RJP van Eekeren, Doeke Boersma, Suzanne Holewijn, Anco Vahl in Trials (2014)

  5. Article

    Open Access

    Mechanochemical endovenous ablation versus radiofrequency ablation in the treatment of primary small saphenous vein insufficiency (MESSI trial): study protocol for a randomized controlled trial

    Minimally invasive endothermal techniques, for example, radiofrequency ablation (RFA), have revolutionized the treatment of insufficient truncal veins and are associated with an excellent outcome. The use of t...

    Doeke Boersma, Ramon RJP van Eekeren, Hans JC Kelder, Debora AB Werson in Trials (2014)