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  1. No Access

    Article

    Multiple chronic lacunes predicting early neurological deterioration and long-term functional outcomes according to TOAST classification in acute ischemic stroke

    Studies regarding multiple chronic lacunes (MCLs) and clinical outcome according to stroke etiology are scarce. We sought to evaluate the association between MCL and short-term/long-term clinical outcomes acco...

    Hyuk-je Lee, Taewon Kim, Jaseong Koo, Young-Do Kim, Seunghee Na in Neurological Sciences (2023)

  2. No Access

    Article

    A clinical study of 288 patients with anterior cerebral artery infarction

    Acute ischemic stroke in the territory of anterior cerebral artery (ACA) is uncommon. Therefore, large population studies evaluating ACA infarction are scarce. We sought to evaluate epidemiological and etiolog...

    Hyunji Cho, Taewon Kim, Young-Do Kim, Seunghee Na, Yun Ho Choi in Journal of Neurology (2022)

  3. No Access

    Article

    Targeted Temperature Management at 36 °C Shows Therapeutic Effectiveness via Alteration of Microglial Activation and Polarization After Ischemic Stroke

    Ischemic injury leads to cell death and inflammatory responses after stroke. Microglia especially play a crucial role in this brain inflammation. Targeted temperature management (TTM) at 33 °C has shown neurop...

    Jong Youl Kim, Ju Hee Kim, Joohyun Park, ** Ho Beom in Translational Stroke Research (2022)

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    Article

    Blood-brain barrier permeability assessed by perfusion computed tomography predicts hemorrhagic transformation in acute reperfusion therapy

    Hemorrhagic transformation (HT) is one of the most feared complications of acute recanalization therapies. The aim of this study was to evaluate whether blood-brain barrier permeability (BBBP) imaging can pred...

    Taewon Kim, Jaseong Koo, Seong-hoon Kim, In-Uk Song in Neurological Sciences (2018)

  5. Article

    Open Access

    A case report of multiple cervical artery dissection after peripheral type facial palsy and use of steroids

    Cervical artery dissection is one of the most important causes of ischemic stroke in young age patients. However, multiple cervical artery dissection simultaneously involving the anterior and posterior circula...

    Sung eun Chung, Tae Hwan Yoon, Kyung Mi Lee, Hyug-Gi Kim, Bum Joon Kim in BMC Neurology (2018)

  6. Article

    Open Access

    Hypothermia inhibits the propagation of acute ischemic injury by inhibiting HMGB1

    Acute ischemic stroke causes significant chronic disability worldwide. We designed this study to clarify the mechanism by which hypothermia helps alleviate acute ischemic stroke. In a middle cerebral artery oc...

    Jung Ho Lee, Eun Jang Yoon, Jeho Seo, Adriana Kavoussi, Yong Eun Chung in Molecular Brain (2016)

  7. Article

    Open Access

    TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity

    Recent studies have indicated that Toll-like receptor 4 (TLR4), a pathogen-recognition receptor that triggers inflammatory signals in innate immune cells, is also expressed on sensory neurons, implicating its ...

    Hyunjung Min, Hyunkyoung Lee, Hyoungsub Lim, Yong Ho Jang in Molecular Brain (2014)

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    Article

    Differences in cerebral perfusion according to phenotypes of essential tremor: brain perfusion SPECT study using SPM analysis

    Essential tremor (ET) is one of the most common movement disorders. However, few studies regarding the differences of pathophysiology according to phenotypes of ET have been reported. We investigated whether ...

    In-Uk Song, Jeong-Wook Park, Sung-Woo Chung, Yong-An Chung in Neurological Sciences (2014)

  9. No Access

    Article

    Orthostatic hypotension, non-dip** and striatal dopamine in Parkinson disease

    Orthostatic hypotension and non-dip** are relatively common autonomic dysfunctions in patients with Parkinson disease (PD). These abnormalities have been thought to occur independently of striatal dopaminerg...

    Yoon-Sang Oh, Joong-Seok Kim, Yong-An Chung, Ie Ryung You in Neurological Sciences (2013)

  10. No Access

    Article

    Association between high-sensitivity C-reactive protein and risk of early idiopathic Parkinson’s disease

    Although neuroinflammation is known to play an important role in the pathogeneses of neurodegenerative diseases, few studies have been conducted on the association between Parkinson’s disease (PD) and high-sen...

    In-Uk Song, Sung-Woo Chung, Joong-Seok Kim, Kwang-Soo Lee in Neurological Sciences (2011)

  11. No Access

    Article

    Diffusion-weighted MR imaging of pyogenic intraventricular empyema

    Pyogenic intraventricular empyema (PIE) is a potentially fatal CNS infection. However, it is sometimes difficult to diagnose PIE on the basis of clinical and conventional MRI findings. Diffusion-weighted imagi...

    Kil-Tae Han, Dae Seob Choi, Jae Wook Ryoo, Jae Min Cho, Kyung Nyeo Jeon in Neuroradiology (2007)