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Article
A new mechanism of thyroid hormone receptor β agonists ameliorating nonalcoholic steatohepatitis by inhibiting intestinal lipid absorption via remodeling bile acid profiles
Excessive dietary calories lead to systemic metabolic disorders, disturb hepatic lipid metabolism, and aggravate nonalcoholic steatohepatitis (NASH). Bile acids (BAs) play key roles in regulating nutrition abs...
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Article
Title – Long term outcomes of vitrectomy and ERM peel: Can pre-operative metamorphopsia measured using the D-Chart help improve surgical candidate selection?
To assess the predictive value of pre-operative metamorphopsia, measured using the D-Chart, in patients undergoing epiretinal membrane (ERM) surgery and how this relates to improvement in quality of life after...
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Article
Four Labdane Diterpenoids from Leonurus japonicus
A new labdane diterpenoid, leojaponotin (1), and three known labdane diterpenoids (2–4), were isolated from Leonurus japonicus. Their structures were elucidated by spectroscopic analysis including NMR and MS.
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Article
Differentiation of closely-related species within Acinetobacter baumannii-calcoaceticus complex via Raman spectroscopy: a comparative machine learning analysis
Bacterial species within the Acinetobacter baumannii-calcoaceticus (Acb) complex are very similar and are difficult to discriminate. Misidentification of these species in human infection may lead to severe conseq...
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Article
Metabolites from Smilax nantoensis with Antioxidant Activity
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Article
Open AccessExploring quantitative measures in metacognition of emotion
Metacognition of emotion (meta-emotion) refers to the ability to evaluate and identify one’s emotional feelings. No previous study has defined and measured this construct through objective and quantitative pro...
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Article
Open AccessPACS plus criteria: a retrospective cohort review of 612 consecutive patients treated with bilateral YAG peripheral iridotomies
With an ageing population and better life expectancy, the prevalence of angle closure disease is expected to increase by 20% per decade. In 2022, the Royal College of Ophthalmologists (RCOphth) issued a guidel...
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Article
CDK12 Promotes the Proliferation, Migration, and Angiogenesis of Gastric Carcinoma via Activating the PI3K/AKT/mTOR Signaling Pathway
Cyclin-dependent kinase 12 (CDK12) has been found to regulate tumor progression. However, its function in gastric carcinoma (GC) remains controversial. This work aimed to explore the exact effect of CDK12 on ...
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Article
The limits of unconscious semantic priming
Semantic information can be accessed unconsciously, yet it remains unclear to what extent unconscious semantic information spreads across association networks. We compared conscious and unconscious semantic pr...
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Article
Long-Read Sequencing Analysis Revealed the Impact of Forest Conversion on Soil Fungal Diversity in Limu Mountain, Hainan
Soil fungi are essential to soil microorganisms that play an important role in the ecosystem’s soil carbon cycle and mineral nutrient transformation. Understanding the structural characteristics and diversity ...
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Article
Adherence to topical glaucoma therapy in patients attending virtual clinics
Poor adherence to medical therapy is a major challenge to the effective treatment of chronic diseases including glaucoma. Potential factors influencing adherence include treatment complexity and patient unders...
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Article
Spatially Small-scale Approach-avoidance Behaviors Allow Learning-free Machine Inference of Object Preferences in Human Minds
Estimating human preference is an essential capability of a social robot. Such a machine Theory of Mind for others’ preferences is studied predominantly under the framework of inverse reinforcement learning, w...
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Article
Recovery of chlorogenic acid from haskap leaves (Lonicera caerulea) using aqueous two-phase extraction
The concept of a biorefinery can be applied to the haskap plant (Lonicera caerulea), where the berries are harvested but the leaves are an under-utilized resource. In this study, aqueous two-phase extraction (ATP...
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Article
Open AccessBlue-light background impairs visual exogenous attention shift
Previous research into the effects of blue light on visual-spatial attention has yielded mixed results due to a lack of properly controlling critical factors like S-cone stimulation, ipRGCs stimulation, and co...
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Article
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice
Promotion of hepatic glycogen synthesis and inhibition of hepatic glucose production are effective strategies for controlling hyperglycemia in type 2 diabetes mellitus (T2DM), but agents with both properties w...
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Chapter and Conference Paper
The Effect of Face-to-Face Interaction on Older Adults’ Attitudes Toward Robots in Human-Computer Interaction
Interpersonal interactions are often expected to be polite and follow communicative norms to avoid potential social conflicts by employing strategies such as face work. Although face work has been well-documen...
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Article
Open AccessDevelopment and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
11β-Hydroxysteroid dehydrogenase 1 (11β-HSD1) represents a promising drug target for metabolic syndrome, including obesity and type 2 diabetes. Our initial screen of a collection of natural products from Danshen ...
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Article
Inferring Stressors from Conversation: Towards an Emotional Support Robot Companion
People build relationships with each other through emotional support. Appropriate care provided by friends or family may critically help people extricate themselves from negative emotional states. In this work...
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Article
Open AccessRobots and Sustainability: Robots as Persuaders to Promote Recycling
Humans tend to interact socially with humanoid devices, such as robots. Therefore, a possible application of robotics technology is the promotion of pro-social behavior, namely recycling. To test the effective...
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Article
A modified transconjunctival technique for botulinum toxin chemodenervation of levator palpebrae superioris for corneal protection
Botulinum toxin (BTX) is useful for inducing temporary ptosis in patients with ocular surface disease. However, transcutaneous BTX often causes inadvertent superior rectus (SR) paresis. Furthermore, Muller’s m...
