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Roles for negative cell regulator 14-3-3σ in control of MDM2 activities

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  1. Article

    Open Access

    Laparoscopic-based perivascular renal sympathetic nerve denervation: a feasibility study in a porcine model

    This study aims to evaluate the effects and safety of laparoscopic-based perivascular renal sympathetic nerve denervation (RDN) in a porcine model fed a high-fat diet.

    Linwei Zhao, Enyong Su, **aohang Yang, Binbin Zhu in European Journal of Medical Research (2020)

  2. Article

    Open Access

    FGF/FGFR signaling in health and disease

    Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR) signaling has crucial roles in a multitude of processes during embryonic development and adult homeostasis by regulating cell...

    Yangli **e, Nan Su, **g Yang, Qiaoyan Tan in Signal Transduction and Targeted Therapy (2020)

  3. Article

    Open Access

    Immunogenicity and safety of NVSI-06-07 as a heterologous booster after priming with BBIBP-CorV: a phase 2 trial

    The increased coronavirus disease 2019 (COVID-19) breakthrough cases pose the need of booster vaccination. We conducted a randomised, double-blinded, controlled, phase 2 trial to assess the immunogenicity and ...

    Nawal Al Kaabi, Yun Kai Yang, **g Zhang, Ke Xu in Signal Transduction and Targeted Therapy (2022)

  4. Article

    Open Access

    LPCAT1 acts as an independent prognostic biomarker correlated with immune infiltration in hepatocellular carcinoma

    Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is overexpressed in multiple human tumors. However, the role of LPCAT1 in hepatocellular carcinoma (HCC) has not been understood. We aim to explore the relati...

    Lan Li, **ao Wang, Yanni Ding, Nini Hui, Bingjie Su in European Journal of Medical Research (2022)

  5. Article

    Open Access

    A kidney-brain neural circuit drives progressive kidney damage and heart failure

    Chronic kidney disease (CKD) and heart failure (HF) are highly prevalent, aggravate each other, and account for substantial mortality. However, the mechanisms underlying cardiorenal interaction and the role of...

    Wei Cao, Zhichen Yang, **aoting Liu in Signal Transduction and Targeted Therapy (2023)

  6. Article

    Open Access

    Phase II study of novel orally PI3Kα/δ inhibitor TQ-B3525 in relapsed and/or refractory follicular lymphoma

    This registration study assessed clinical outcomes of TQ-B3525, the dual phosphatidylinositol-3-kinase (PI3K) α/δ inhibitor, in relapsed and/or refractory follicular lymphoma (R/R FL). This phase II study (Cli...

    Huaqing Wang, Jifeng Feng, Yanyan Liu in Signal Transduction and Targeted Therapy (2024)