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  1. Article

    Open Access

    FFAR1 activation attenuates histamine-induced myosin light chain phosphorylation and cortical tension development in human airway smooth muscle cells

    Activation of free fatty acid receptors (FFAR1 and FFAR4) which are G protein-coupled receptors (GPCRs) with established (patho)physiological roles in a variety of obesity-related disorders, induce human airwa...

    Shengjie Xu, Anthony Schwab, Nikhil Karmacharya, Gaoyuan Cao… in Respiratory Research (2020)

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  2. Article

    Open Access

    A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged high-throughput biophysical screening

    A newly identified mechanism of smooth muscle relaxation is the interaction between the small heat shock protein 20 (HSP20) and 14-3-3 proteins. Focusing upon this class of interactions, we describe here a nov...

    Steven S An, Peter S Askovich, Thomas I Zarembinski, Kwangmi Ahn… in Respiratory Research (2011)

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