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Crystal structure at 1.7 Å of the bovine papillomavirus-1 E2 DMA-binding domain bound to its DNA target

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    Open Access

    The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3

    p53 mutations with single amino acid changes in cancer often lead to dominant oncogenic changes. Here, we have developed a mouse model of gain-of-function (GOF) p53-driven lung cancer utilizing conditionally a...

    Catherine A. Vaughan, Shilpa Singh, Mark A. Subler… in Nature Communications (2021)

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