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Article
Open AccessBPG: Seamless, automated and interactive visualization of scientific data
We introduce BPG, a framework for generating publication-quality, highly-customizable plots in the R statistical environment.
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Article
Open AccessCompendium of TCDD-mediated transcriptomic response datasets in mammalian model systems
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is the most potent congener of the dioxin class of environmental contaminants. Exposure to TCDD causes a wide range of toxic outcomes, ranging from chloracne to acute le...
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Article
Open AccessVennDiagramWeb: a web application for the generation of highly customizable Venn and Euler diagrams
Visualization of data generated by high-throughput, high-dimensionality experiments is rapidly becoming a rate-limiting step in computational biology. There is an ongoing need to quickly develop high-quality v...
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Article
Open AccessMale and female mice show significant differences in hepatic transcriptomic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin
2,3,7,8–tetrachlorodibenzo-p-dixion (TCDD) is the most potent of the dioxin congeners, capable of causing a wide range of toxic effects across numerous animal models. Previous studies have demonstrated that males...
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Article
Open AccessCross-species transcriptomic analysis elucidates constitutive aryl hydrocarbon receptor activity
Research on the aryl hydrocarbon receptor (AHR) has largely focused on variations in toxic outcomes resulting from its activation by halogenated aromatic hydrocarbons. But the AHR also plays key roles in regul...