3 Result(s)
within
Stanley G. Sawicki
Biomedicine
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Chapter
Coronavirus Genome Replication
Viruses belonging to the family Coronaviridae are unique among RNA viruses because of the unusually large size of their genome, which is of messenger- or positive- or plus-sense. It is ∼30,000 bases or 2–3 tim...
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Chapter
Coronaviruses use Discontinuous Extension for Synthesis of Subgenome-Length Negative Strands
We have developed a new model for coronavirus transcription, which we call discontinuous extension, to explain how subgenome-length negatives stands are derived directly from the genome. The current model call...
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Chapter
Characterization of a Small Plaque Mutant of the A59 Strain of Mouse Hepatitis Virus Defective in Cell Fusion
The virions of murine coronaviruses contain nucleocapsid protein and two membrane associated proteins E1 and E2. E2 or S glycoprotein forms the peplomer or spike protein and, as shown by Lawrence Sturman and K...
