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Article
Open AccessRGmatch: matching genomic regions to proximal genes in omics data integration
The integrative analysis of multiple genomics data often requires that genome coordinates-based signals have to be associated with proximal genes. The relative location of a genomic region with respect to the ...
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Article
Open AccessUnderstanding disease mechanisms with models of signaling pathway activities
Understanding the aspects of the cell functionality that account for disease or drug action mechanisms is one of the main challenges in the analysis of genomic data and is on the basis of the future implementa...
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Article
Open AccessPathway network inference from gene expression data
The development of high-throughput omics technologies enabled genome-wide measurements of the activity of cellular elements and provides the analytical resources for the progress of the Systems Biology discipl...
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Article
Open AccessFunctional assessment of time course microarray data
Time-course microarray experiments study the progress of gene expression along time across one or several experimental conditions. Most developed analysis methods focus on the clustering or the differential ex...