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    Article

    Reduced efficacy of blood pressure lowering drugs in the presence of diabetes mellitus—results from the TRIUMPH randomised controlled trial

    We investigated whether diabetes mellitus (DM) affects the efficacy of a low-dose triple combination pill and usual care among people with mild-moderate hypertension. TRIUMPH (TRIple pill vs Usual care Managem...

    Sonali R. Gnanenthiran, Ruth Webster, Asita de Silva in Hypertension Research (2023)

  2. Article

    Open Access

    Wisdom of the Crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies

    In a first of its kind assessment in cardiovascular research, we assessed whether pooled cardiovascular expertise could accurately predict efficacy and tolerability for both a novel and an established treatmen...

    Sonali R. Gnanenthiran, Vivekanand Jha, Abdul Salam in Journal of Human Hypertension (2023)

  3. Article

    Open Access

    The effect of salt substitution on frequency and severity of headache: results from the SSaSS cluster-randomised controlled trial of 20,995 participants

    Headache is one of the most common neurological symptoms. Headache disorders are associated with a high global burden of disease. Prior studies indicate that short-to-medium term sodium reduction reduces heada...

    Faraidoon Haghdoost, Sonali R. Gnanenthiran in European Journal of Clinical Nutrition (2024)

  4. Article

    Open Access

    The Pathophysiology, Prognosis and Treatment of Hypertension in Females from Pregnancy to Post-menopause: A Review

    We summarise the physiological changes and risk factors for hypertension in females, potential sex-specific management approaches, and long-term prognosis.

    Simeng Li, Isabella Tan, Emily Atkins, Aletta E Schutte in Current Heart Failure Reports (2024)